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NCT03361189 · ClinicalTrials.gov registry record · Phase 2

Specialized Pacing for Patients With Congenital Heart Disease

A Phase 2 study, sponsored by University of California, Los Angeles.

Terminated
Registry status
Phase 2
Development phase
4
Enrollment target

NCT03361189 is a Phase 2 study that was terminated before completion, run by University of California, Los Angeles. The registered enrollment target is 4 participants.

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The verdict

NCT03361189, a Phase 2 study, was terminated before completion, sponsored by University of California, Los Angeles.

TERMINATED
Registry status
Phase 2
Development phase
4 participants
Enrollment target

Study Summary

The closed-loop stimulation (CLS) algorithm is a novel sensor-based technology that relies on the change in myocardial systolic impedance for modulation of the heart rate during physical and emotional stress.3 The pacing algorithm has been shown to be highly effective for a wide range of clinical scenarios. Despite the fact that congenital heart disease (CHD) patients are likely to derive significant benefit in terms of functional ability and aerobic capacity using this novel technology, the CLS system has not been adequately studied in this population. As many CHD patients also undergo epicardial placement of pacing systems at the time of concomitant cardiac surgery, CLS has been less often utilized in this population given almost no data in the setting of surgical electrode placement. The present study intends to examine the benefits of the CLS algorithm in the CHD population, employing the use of epicardial pacemaker systems in the study protocol.

Interventions

  • DEVICE Closed loop stimulation
  • DEVICE Standard rate response

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2021-05-09
Est. Completion 2021-11-03
Phase Phase 2

What the Registry Record Tells You About NCT03361189

The ClinicalTrials.gov registry entry for NCT03361189 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Closed loop stimulation is the first listed.

NCT03361189 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03361189 about?

NCT03361189 is a clinical study titled "Specialized Pacing for Patients With Congenital Heart Disease". The closed-loop stimulation (CLS) algorithm is a novel sensor-based technology that relies on the change in myocardial systolic impedance for modulation of the heart rate during physical and emotional stress.3 The pacing algorithm has been shown to be highly effective for a wide range of clinical sc...

What is the current status of trial NCT03361189?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2021-05-09. Estimated completion is 2021-11-03.

What interventions are being tested in trial NCT03361189?

The interventions under investigation include: Closed loop stimulation (DEVICE), Standard rate response (DEVICE).

Who is sponsoring clinical trial NCT03361189?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.