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NCT03357627 · ClinicalTrials.gov registry record · Phase 1

A Study of TAK-659 in Combination With Venetoclax for Adult Participants With Previously Treated Non-Hodgkin Lymphoma

A Phase 1 study, sponsored by Calithera Biosciences.

Completed
Registry status
Phase 1
Development phase
43
Enrollment target

NCT03357627 is a Phase 1 study that has completed, run by Calithera Biosciences. The registered enrollment target is 43 participants.

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The verdict

NCT03357627, a Phase 1 study, has completed, sponsored by Calithera Biosciences.

COMPLETED
Registry status
Phase 1
Development phase
43 participants
Enrollment target

Study Summary

The purpose of this study is to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of TAK-659 and venetoclax when administered in combination in participants with non-Hodgkin lymphoma (NHL) relapsed and/or refractory after at least 1 prior line of therapy and to evaluate safety and tolerability of TAK-659 and venetoclax when administered in combination.

Interventions

  • DRUG Venetoclax
  • DRUG TAK-659

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2018-02-16
Est. Completion 2021-08-03
Phase Phase 1

Sponsor

Calithera Biosciences

22 total trials

What the Registry Record Tells You About NCT03357627

The ClinicalTrials.gov registry entry for NCT03357627 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Calithera Biosciences, which has 22 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Venetoclax is the first listed.

NCT03357627 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03357627 about?

NCT03357627 is a clinical study titled "A Study of TAK-659 in Combination With Venetoclax for Adult Participants With Previously Treated Non-Hodgkin Lymphoma". The purpose of this study is to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of TAK-659 and venetoclax when administered in combination in participants with non-Hodgkin lymphoma (NHL) relapsed and/or refractory after at least 1 prior line of therapy and to evalua...

What is the current status of trial NCT03357627?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 43 participants. The study started on 2018-02-16. Estimated completion is 2021-08-03.

What interventions are being tested in trial NCT03357627?

The interventions under investigation include: Venetoclax (DRUG), TAK-659 (DRUG).

Who is sponsoring clinical trial NCT03357627?

This trial is sponsored by Calithera Biosciences, which has 22 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.