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NCT03345082 · ClinicalTrials.gov registry record · Phase 2

A Dose Ranging Study of OPT-302 With Ranibizumab in Neovascular (Wet) AMD

A Phase 2 study, sponsored by Opthea Limited.

Completed
Registry status
Phase 2
Development phase
366
Enrollment target

NCT03345082 is a Phase 2 study that has completed, run by Opthea Limited. The registered enrollment target is 366 participants.

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The verdict

NCT03345082, a Phase 2 study, has completed, sponsored by Opthea Limited.

COMPLETED
Registry status
Phase 2
Development phase
366 participants
Enrollment target

Study Summary

A multicentre, randomised, parallel group, sham-controlled, double-masked, dose-ranging study, investigating two doses of OPT-302 in combination with ranibizumab compared with ranibizumab with sham, over six consecutive monthly dosing cycles in participants with neovascular (wet) AMD.

Interventions

  • BIOLOGICAL ranibizumab
  • BIOLOGICAL OPT-302
  • OTHER sham intravitreal injection

Trial Details

FieldValue
Enrollment Target 366 participants
Start Date 2017-11-06
Est. Completion 2019-05-14
Phase Phase 2

Sponsor

Opthea Limited

5 total trials

What the Registry Record Tells You About NCT03345082

The ClinicalTrials.gov registry entry for NCT03345082 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 366 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Opthea Limited, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which ranibizumab is the first listed.

NCT03345082 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03345082 about?

NCT03345082 is a clinical study titled "A Dose Ranging Study of OPT-302 With Ranibizumab in Neovascular (Wet) AMD". A multicentre, randomised, parallel group, sham-controlled, double-masked, dose-ranging study, investigating two doses of OPT-302 in combination with ranibizumab compared with ranibizumab with sham, over six consecutive monthly dosing cycles in participants with neovascular (wet) AMD.

What is the current status of trial NCT03345082?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 366 participants. The study started on 2017-11-06. Estimated completion is 2019-05-14.

What interventions are being tested in trial NCT03345082?

The interventions under investigation include: ranibizumab (BIOLOGICAL), OPT-302 (BIOLOGICAL), sham intravitreal injection (OTHER).

Who is sponsoring clinical trial NCT03345082?

This trial is sponsored by Opthea Limited, which has 5 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.