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NCT03344250 · ClinicalTrials.gov registry record · Phase 1

Phase I EGFR BATs in Newly Diagnosed Glioblastoma

A Phase 1 study, sponsored by University of Virginia.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target

NCT03344250 is a Phase 1 study that has completed, run by University of Virginia. The registered enrollment target is 16 participants.

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The verdict

NCT03344250, a Phase 1 study, has completed, sponsored by University of Virginia.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target

Study Summary

This is a phase I trial using EGFR Bi-armed Activated T-cells (BATs) in combination with standard of care temozolomide (TMZ) and radiation (RT) in patients with glioblastoma (GBM). The purpose of the study is to determine a safe dose of EGFR BATs when given with standard of care therapy.

Interventions

  • DRUG EGFR BATs with TMZ following SOC RT/TMZ
  • DRUG Weekly EGFR BATs following SOC RT/TMZ

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2018-03-01
Est. Completion 2023-05-08
Phase Phase 1

Sponsor

University of Virginia

449 total trials

What the Registry Record Tells You About NCT03344250

The ClinicalTrials.gov registry entry for NCT03344250 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Virginia, which has 449 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which EGFR BATs with TMZ following SOC RT/TMZ is the first listed.

NCT03344250 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03344250 about?

NCT03344250 is a clinical study titled "Phase I EGFR BATs in Newly Diagnosed Glioblastoma". This is a phase I trial using EGFR Bi-armed Activated T-cells (BATs) in combination with standard of care temozolomide (TMZ) and radiation (RT) in patients with glioblastoma (GBM). The purpose of the study is to determine a safe dose of EGFR BATs when given with standard of care therapy.

What is the current status of trial NCT03344250?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2018-03-01. Estimated completion is 2023-05-08.

What interventions are being tested in trial NCT03344250?

The interventions under investigation include: EGFR BATs with TMZ following SOC RT/TMZ (DRUG), Weekly EGFR BATs following SOC RT/TMZ (DRUG).

Who is sponsoring clinical trial NCT03344250?

This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.