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NCT03330795 · ClinicalTrials.gov registry record · Phase 1
Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant
A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- Phase 1
- Development phase
- 5
- Enrollment target
NCT03330795: Completed Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT03330795 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 5 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03330795, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 5 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether bilateral orthotopic lung transplantation (BOLT) followed by cadaveric partially-matched CD3+/CD19+ depleted bone marrow transplant (BMT) is safe and effective for individuals aged 10 through 45 years with the diagnosis of primary immunodeficiency (PID) and end-stage lung disease. The enrollment goal: 8 participants who receive both BOLT and BMT.
Primary Outcome
How many, if any, participants die during study participation.
Interventions
- BIOLOGICAL CD3/CD19 neg allogeneic BMT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2017-12-01 |
| Est. Completion | 2024-03-01 |
| Phase | Phase 1 |
What the finished NCT03330795 record still lists
NCT03330795 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which CD3/CD19 neg allogeneic BMT is the first listed.
NCT03330795 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03330795 about?
NCT03330795 is a clinical study titled "Bilateral Orthotopic Lung Transplant - Bone Marrow Transplant". The purpose of this study is to determine whether bilateral orthotopic lung transplantation (BOLT) followed by cadaveric partially-matched CD3+/CD19+ depleted bone marrow transplant (BMT) is safe and effective for individuals aged 10 through 45 years with the diagnosis of primary immunodeficiency (P...
What is the current status of trial NCT03330795?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2017-12-01. Estimated completion is 2024-03-01.
What interventions are being tested in trial NCT03330795?
The interventions under investigation include: CD3/CD19 neg allogeneic BMT (BIOLOGICAL).
Who is sponsoring clinical trial NCT03330795?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03330795's enrollment target sits among peer trials
5 1989th of 2000 higher than 6 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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