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NCT03316963 · ClinicalTrials.gov registry record · Early Phase 1
Neostigmine For Snoring During DISE
A Early Phase 1 study, sponsored by Emory University.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 1
- Enrollment target
NCT03316963: Clinical Trial Early Phase 1 study, sponsored by Emory University.
NCT03316963 is a Early Phase 1 study that was terminated before completion, run by Emory University. The registered enrollment target is 1 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03316963, a Early Phase 1 study, was terminated before completion, sponsored by Emory University.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 1 participants
- Enrollment target
Study Summary
The study team is seeking a novel treatment for snoring involving local application of a nerve stimulant medication, neostigmine. In this study, neostigmine will be injected into 5 sites of the soft palate during a standard procedure, drug-induced sleep endoscopy, to evaluate the effect on snoring.
Primary Outcome
The data will come from the drug-induced sleep endoscopy (DISE) audio and video recordings. Prior to the neostigmine injection, a snoring microphone will be placed over the right clavicle. Following administration of neostigmine, the patient will be observed for an additional 4 minutes to examine sound emanating from the soft palate. Total run time, instantaneous decibel levels, LAeq (average decibel level over time), and the maximum decibel level will be recorded.
Interventions
- DRUG Neostigmine Methylsulfate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2017-11-14 |
| Est. Completion | 2019-03-19 |
| Phase | Early Phase 1 |
Why NCT03316963 stopped before completion
NCT03316963 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Neostigmine Methylsulfate is the first listed.
NCT03316963 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03316963 about?
NCT03316963 is a clinical study titled "Neostigmine For Snoring During DISE". The study team is seeking a novel treatment for snoring involving local application of a nerve stimulant medication, neostigmine. In this study, neostigmine will be injected into 5 sites of the soft palate during a standard procedure, drug-induced sleep endoscopy, to evaluate the effect on snoring.
What is the current status of trial NCT03316963?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 1 participants. The study started on 2017-11-14. Estimated completion is 2019-03-19.
What interventions are being tested in trial NCT03316963?
The interventions under investigation include: Neostigmine Methylsulfate (DRUG).
Who is sponsoring clinical trial NCT03316963?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03316963's enrollment target sits among peer trials
1 1985th of 2000 the lowest of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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