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NCT03316118 · ClinicalTrials.gov registry record · Phase 4
US Guided GNB vs Saline Injection for TKA
A Phase 4 study, sponsored by Northwestern University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 2
- Enrollment target
NCT03316118: Clinical Trial Phase 4 study, sponsored by Northwestern University.
NCT03316118 is a Phase 4 study that was terminated before completion, run by Northwestern University. The registered enrollment target is 2 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03316118, a Phase 4 study, was terminated before completion, sponsored by Northwestern University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 2 participants
- Enrollment target
Study Summary
Do ultrasound-guided genicular nerve blocks with 0.5% bupivacaine provide improved knee analgesia for patients recovering from total knee replacement surgery compared to saline injection? Hypotheses: The investigators hypothesize that the combination of ultrasound-guided adductor canal block (ACB) and genicular nerve block will achieve lower opioid consumption and therefore lead to decreased systemic side effects and improved overall satisfaction compared to ultrasound-guided saline injection for patients undergoing minimally invasive elective total knee arthroplasty (TKA).
Primary Outcome
Post-operative opioid consumption measured in morphine milligram equivalents (MME)during the hospital stay up to 36 hours after surgery.
Interventions
- DRUG saline
- DRUG bupivacaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2017-10-05 |
| Est. Completion | 2021-06-21 |
| Phase | Phase 4 |
Why NCT03316118 stopped before completion
NCT03316118 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which saline is the first listed.
NCT03316118 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03316118 about?
NCT03316118 is a clinical study titled "US Guided GNB vs Saline Injection for TKA". Do ultrasound-guided genicular nerve blocks with 0.5% bupivacaine provide improved knee analgesia for patients recovering from total knee replacement surgery compared to saline injection? Hypotheses: The investigators hypothesize that the combination of ultrasound-guided adductor canal block (ACB)...
What is the current status of trial NCT03316118?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 2 participants. The study started on 2017-10-05. Estimated completion is 2021-06-21.
What interventions are being tested in trial NCT03316118?
The interventions under investigation include: saline (DRUG), bupivacaine (DRUG).
Who is sponsoring clinical trial NCT03316118?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03316118's enrollment target sits among peer trials
2 1998th of 2000 higher than 1 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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