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NCT03306875 · ClinicalTrials.gov registry record · NA
Impact of Brain Connectome and Personality on Cognitive Rehabilitation in Multiple Sclerosis
A NA study, sponsored by State University of New York at Buffalo.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT03306875: Completed NA study, sponsored by State University of New York at Buffalo.
NCT03306875 is a NA study that has completed, run by State University of New York at Buffalo. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03306875, a NA study, has completed, sponsored by State University of New York at Buffalo.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
This study aims to apply baseline MRI and neuropsychological measures to predict patient responses to behavioral cognitive rehabilitation. Training will take place over 12 weeks, 1 hour per day, 5 days per week. The investigator hypothesizes the following: \[1a\] The investigator expects that individuals with low baseline Conscientiousness will experience a lower magnitude of overall cognitive improvement following rehabilitation 1. b\] The investigator expects the impact of Conscientiousness on fidelity of rehabilitation will in part be moderated by individual differences in program adherence and executive function 2. a\] The investigator expects that individual differences in structural and functional connectome disturbances will in part explain differences in participant responses to cognitive rehabilitation. This study will also serve to supplement the sample of participants for the current IRB approved study ((IRB: 603069, Title: A case-control, 5-year follow-up study of cardiovascular, environmental and genetic risk factors for disease progression in patients with multiple sclerosis.
Primary Outcome
The investigator expects baseline Conscientiousness to correlate positively with cognitive gains following rehabilitation. Conscientiousness will be measured using the NEO-Five Factor Inventory (NEOFFI). All scores for personality testing will be converted to age-corrected t-scores for final analysis. These are therefore standardized values without units.
Interventions
- BEHAVIORAL Cognitive Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2017-11-01 |
| Est. Completion | 2018-10-20 |
| Phase | NA |
What the finished NCT03306875 record still lists
NCT03306875 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which Cognitive Training is the first listed.
NCT03306875 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03306875 about?
NCT03306875 is a clinical study titled "Impact of Brain Connectome and Personality on Cognitive Rehabilitation in Multiple Sclerosis". This study aims to apply baseline MRI and neuropsychological measures to predict patient responses to behavioral cognitive rehabilitation. Training will take place over 12 weeks, 1 hour per day, 5 days per week. The investigator hypothesizes the following: \[1a\] The investigator expects that indi...
What is the current status of trial NCT03306875?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2017-11-01. Estimated completion is 2018-10-20.
What interventions are being tested in trial NCT03306875?
The interventions under investigation include: Cognitive Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT03306875?
This trial is sponsored by State University of New York at Buffalo, which has 243 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03306875's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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