Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03304132 · ClinicalTrials.gov registry record
The Oral Microbiome and Upper Aerodigestive Squamous Cell Cancer
A clinical trial, sponsored by NYU Langone Health.
- Completed
- Registry status
- 560
- Enrollment target
NCT03304132: Completed study, sponsored by NYU Langone Health.
NCT03304132 is a clinical trial that has completed, run by NYU Langone Health. The registered enrollment target is 560 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03304132 has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- 560 participants
- Enrollment target
Study Summary
The human oral cavity is a diverse habitat that contains approximately 700 prokaryotic species. The oral microbiome is comprised of 44% named species, 12% isolates representing unnamed species, and 44% phylotypes known only from 16S rRNA based cloning studies (http://www.homd.org/). Species from 11 phyla have been identified: Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria, Spirochaetes, Fusobacteria, TM7, Synergistetes, Chlamydiae, Chloroflexi and SR1 (http://www.homd.org/). Because these observations have been mainly based on data generated from traditional Sanger sequencing, the diversity of oral microbiome is highly likely underestimated. Application of high throughput sequencing to the oral microbiome similar to the scale of the microbiome studies of other body sites (GI tract, skin, and vagina) under the Human Microbiome Project is necessary to obtain data essential for understanding the diversity and community structure of the oral microbiome in health and disease.
Primary Outcome
Data alignment and clustering to determine microbiome species diversity
Interventions
- OTHER Classification of Oral Microbiome Using 16S rRNA gene sequence-based approach
- OTHER Classification of Oral Microbiome Using taxonomic approach
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 560 participants |
| Start Date | 1992-12-01 |
| Est. Completion | 2010-12-01 |
What the finished NCT03304132 record still lists
NCT03304132 is an observational study that tracks outcomes without assigning an intervention. The registered 560 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 2 interventions - of which Classification of Oral Microbiome Using 16S rRNA gene sequence-based approach is the first listed.
NCT03304132 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03304132 about?
NCT03304132 is a clinical study titled "The Oral Microbiome and Upper Aerodigestive Squamous Cell Cancer". The human oral cavity is a diverse habitat that contains approximately 700 prokaryotic species. The oral microbiome is comprised of 44% named species, 12% isolates representing unnamed species, and 44% phylotypes known only from 16S rRNA based cloning studies (http://www.homd.org/). Species from 11 ...
What is the current status of trial NCT03304132?
This trial is currently completed. The enrollment target is 560 participants. The study started on 1992-12-01. Estimated completion is 2010-12-01.
What interventions are being tested in trial NCT03304132?
The interventions under investigation include: Classification of Oral Microbiome Using 16S rRNA gene sequence-based approach (OTHER), Classification of Oral Microbiome Using taxonomic approach (OTHER).
Who is sponsoring clinical trial NCT03304132?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04661358 · 560 participants · Phase 3
Fenofibrate for Prevention of DR Worsening
- NCT05473871 · 560 participants · NA
Enhancing Capacity in Churches to Implement PA Programs
- NCT06001541 · 560 participants · NA
Web-based Program to Improve Self-management Among Veterans-caregiver Dyads
- NCT06246916 · 560 participants · Phase 3
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI