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NCT03302845 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects
A Phase 1 study, sponsored by Lexicon Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
NCT03302845: Completed Phase 1 study, sponsored by Lexicon Pharmaceuticals.
NCT03302845 is a Phase 1 study that has completed, run by Lexicon Pharmaceuticals. The registered enrollment target is 32 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03302845, a Phase 1 study, has completed, sponsored by Lexicon Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
Study Summary
This drug-drug interaction study will evaluate the impact of two different acid reducing agents (from two different drug classes) co-administered with a single dose of telotristat ethyl.
Primary Outcome
Maximum observed concentration of telotristat ethyl
Interventions
- DRUG Omeprazole 40 MG
- DRUG Famotidine 40 mg
- DRUG Telotristat ethyl 250 mg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2017-09-21 |
| Est. Completion | 2017-11-07 |
| Phase | Phase 1 |
What the finished NCT03302845 record still lists
NCT03302845 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 3 interventions - of which Omeprazole 40 MG is the first listed.
NCT03302845 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03302845 about?
NCT03302845 is a clinical study titled "A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects". This drug-drug interaction study will evaluate the impact of two different acid reducing agents (from two different drug classes) co-administered with a single dose of telotristat ethyl.
What is the current status of trial NCT03302845?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2017-09-21. Estimated completion is 2017-11-07.
What interventions are being tested in trial NCT03302845?
The interventions under investigation include: Omeprazole 40 MG (DRUG), Famotidine 40 mg (DRUG), Telotristat ethyl 250 mg (DRUG).
Who is sponsoring clinical trial NCT03302845?
This trial is sponsored by Lexicon Pharmaceuticals, which has 56 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03302845's enrollment target sits among peer trials
32 1296th of 2000 higher than 679 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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