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NCT03300258 · ClinicalTrials.gov registry record · NA
Robotic Pedaling Therapy for Targeted Neural Plasticity
A NA study, sponsored by University of Wisconsin, Madison.
- Terminated
- Registry status
- NA
- Development phase
- 44
- Enrollment target
NCT03300258: Clinical Trial NA study, sponsored by University of Wisconsin, Madison.
NCT03300258 is a NA study that was terminated before completion, run by University of Wisconsin, Madison. The registered enrollment target is 44 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03300258, a NA study, was terminated before completion, sponsored by University of Wisconsin, Madison.
- TERMINATED
- Registry status
- NA
- Development phase
- 44 participants
- Enrollment target
Study Summary
The aim of this Pilot study is to determine whether robotically targeted lower-limb pedaling therapy can increase the extent of stroke recovery on behavioral measures and induce brain plasticity as measured by functional magnetic resonance imaging (fMRI). Forty (40) adult stroke patients and 80 healthy controls will be enrolled in this study. Of the 40 patients, half will be randomly assigned to the robotically-targeted training ("robotic") group and will receive training on the targeted training task. The other half of the patients will perform a duration-matched aerobic pedaling exercise ("control" group). All stroke patients will be scanned before and after their training program while performing or imagining simple motor tasks. Behavioral assessments of motor and cognitive capacities will be collected at each timepoint. Healthy control subjects enrolled for device testing (20) will receive up to 5 training sessions in a modified robotic paradigm and 1 fMRI scan, in order to investigate motor learning and brain activity in a novel motor control task. Additional healthy pilot subjects (up to 60) will test training protocols and assessments during preparatory design phases of the project.
Primary Outcome
A simple series of laps along a 30 m straight path in a level hallway.
Interventions
- DEVICE Robotic therapy
- DEVICE Aerobic therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2019-06-01 |
| Est. Completion | 2022-06-29 |
| Phase | NA |
Why NCT03300258 stopped before completion
NCT03300258 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Robotic therapy is the first listed.
NCT03300258 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03300258 about?
NCT03300258 is a clinical study titled "Robotic Pedaling Therapy for Targeted Neural Plasticity". The aim of this Pilot study is to determine whether robotically targeted lower-limb pedaling therapy can increase the extent of stroke recovery on behavioral measures and induce brain plasticity as measured by functional magnetic resonance imaging (fMRI). Forty (40) adult stroke patients and 80 heal...
What is the current status of trial NCT03300258?
This trial is currently terminated. It is a NA study. The enrollment target is 44 participants. The study started on 2019-06-01. Estimated completion is 2022-06-29.
What interventions are being tested in trial NCT03300258?
The interventions under investigation include: Robotic therapy (DEVICE), Aerobic therapy (DEVICE).
Who is sponsoring clinical trial NCT03300258?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03300258's enrollment target sits among peer trials
44 1423rd of 2000 higher than 566 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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