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NCT03293004 · ClinicalTrials.gov registry record · NA
Collagen Vitamin C Dose Response Performance
A NA study, sponsored by University of California, Davis.
- Completed
- Registry status
- NA
- Development phase
- 23
- Enrollment target
NCT03293004 is a NA study that has completed, run by University of California, Davis. The registered enrollment target is 23 participants.
The verdict
NCT03293004, a NA study, has completed, sponsored by University of California, Davis.
- COMPLETED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
Study Summary
Previous work has shown that gelatin supplementation could increase collagen synthesis in humans. In this study subjects consume placebo, 5 or 15 g of gelatin with a standard amount of vitamin C (48 mg) 1 hour before 6 minutes of jump rope exercise. The feeding and exercise intervention was repeated every 6 hours while the subjects were awake for three days and the amount of the amino terminal procollagen I peptide (PINP) was determined; a marker of collagen synthesis, in the blood. Consistent with the hypothesis that gelatin increases collagen synthesis in humans; the amount of PINP in the 15 g gelatin group was significantly higher than either the placebo or the 5 g groups. These data conclusively demonstrate that gelatin supplementation can increase exercise-induced collagen synthesis in humans. Hydrolyzed collagen has a similar amino acid profile, in particular with high concentrations of glycine, proline, hydroxyproline, and arginine. Thus the current study aims to precisely map out the dose response relationship of hydrolyzed collagen and vitamin C on PINP and to determine the optimal dose to achieve maximal increased in PINP levels.
Interventions
- DIETARY_SUPPLEMENT Vitamin C
- DIETARY_SUPPLEMENT Gummy Placebo
- DIETARY_SUPPLEMENT Hydrolyzed collagen
- DIETARY_SUPPLEMENT Optimized Hydrolyzed Collagen and Vitamin C
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2017-09-13 |
| Est. Completion | 2018-05-24 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03293004
The ClinicalTrials.gov registry entry for NCT03293004 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Vitamin C is the first listed.
NCT03293004 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03293004 about?
NCT03293004 is a clinical study titled "Collagen Vitamin C Dose Response Performance". Previous work has shown that gelatin supplementation could increase collagen synthesis in humans. In this study subjects consume placebo, 5 or 15 g of gelatin with a standard amount of vitamin C (48 mg) 1 hour before 6 minutes of jump rope exercise. The feeding and exercise intervention was repeated...
What is the current status of trial NCT03293004?
This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2017-09-13. Estimated completion is 2018-05-24.
What interventions are being tested in trial NCT03293004?
The interventions under investigation include: Vitamin C (DIETARY_SUPPLEMENT), Gummy Placebo (DIETARY_SUPPLEMENT), Hydrolyzed collagen (DIETARY_SUPPLEMENT), Optimized Hydrolyzed Collagen and Vitamin C (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03293004?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
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