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NCT03291743 · ClinicalTrials.gov registry record · NA
The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives
A NA study, sponsored by Carilion Clinic.
- Terminated
- Registry status
- NA
- Development phase
- 38
- Enrollment target
NCT03291743: Clinical Trial NA study, sponsored by Carilion Clinic.
NCT03291743 is a NA study that was terminated before completion, run by Carilion Clinic. The registered enrollment target is 38 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03291743, a NA study, was terminated before completion, sponsored by Carilion Clinic.
- TERMINATED
- Registry status
- NA
- Development phase
- 38 participants
- Enrollment target
Study Summary
Pursuing very early diagnosis is standard of care for several diseases including colon cancer, diabetes and liver disease where an early and aggressive diagnostic and therapeutic approach has been shown to change their natural history. Crohn's disease \[CD\] still lags since commonly at presentation CD has already run a long course, often responding poorly to therapy or requiring surgery. This innovative project proposes a minimally invasive strategy - capsule endoscopy-based screening of first degree relatives \[FDR's\] of CD patients - to develop tools to diagnose CD at or near its biologic onset.
Primary Outcome
This study will screen asymptomatic, first-degree relatives of patients with established Crohn's Disease to detect the disease at or near its biologic onset.
Interventions
- DEVICE Capsule endoscopy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2017-02-10 |
| Est. Completion | 2022-09-30 |
| Phase | NA |
Why NCT03291743 stopped before completion
NCT03291743 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Capsule endoscopy is the first listed.
NCT03291743 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03291743 about?
NCT03291743 is a clinical study titled "The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives". Pursuing very early diagnosis is standard of care for several diseases including colon cancer, diabetes and liver disease where an early and aggressive diagnostic and therapeutic approach has been shown to change their natural history. Crohn's disease \[CD\] still lags since commonly at presentation...
What is the current status of trial NCT03291743?
This trial is currently terminated. It is a NA study. The enrollment target is 38 participants. The study started on 2017-02-10. Estimated completion is 2022-09-30.
What interventions are being tested in trial NCT03291743?
The interventions under investigation include: Capsule endoscopy (DEVICE).
Who is sponsoring clinical trial NCT03291743?
This trial is sponsored by Carilion Clinic, which has 45 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03291743's enrollment target sits among peer trials
38 1538th of 2000 higher than 461 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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