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NCT03287336 · ClinicalTrials.gov registry record · Phase 2
Prevention of Postpartum Hemorrhage With Tranexamic Acid
A Phase 2 study of Postpartum Hemorrhage, sponsored by George Washington University.
- Completed
- Registry status
- Phase 2
- Development phase
- 43
- Enrollment target
- 1
- Study location
NCT03287336: Completed Phase 2 study of Postpartum Hemorrhage, sponsored by George Washington University.
NCT03287336 is a Phase 2 study of Postpartum Hemorrhage that has completed, run by George Washington University. The registered enrollment target is 43 participants, below the 778-participant average among 19 other Postpartum Hemorrhage trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03287336, a Phase 2 study of Postpartum Hemorrhage, has completed, sponsored by George Washington University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 43 participants
- Enrollment target
- 1
- Study location
Study Summary
Postpartum hemorrhage is a significant contributor to maternal morbidity and mortality and is worldwide. TXA has recently been proven to reduce mortality when given to women in setting of diagnosed PPH. US obstetricians and anesthesiologists are hesitant to use TXA in the peripartum period especially for prevention of PPH due to uncertainty of an optimal dose and safety profile. The purpose of this study is to characterize the pharmacokinetics of TXA when given prophylactically at time of delivery. In addition investigators will determine the pharmacodynamics of TXA in the peripartum period.
Primary Outcome
Data obtained from assays of TXA in blood, dose group and patient characteristics; parameter estimates in 2 compartment model includes the clearance of the drug (L/hr).
Conditions Studied
Interventions
- DRUG Tranexamic Acid
Study Locations (1)
District of Columbia
- James Slota - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2018-01-02 |
| Est. Completion | 2023-09-30 |
| Phase | Phase 2 |
What the finished NCT03287336 record still lists
NCT03287336 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 778-participant average among 19 other Postpartum Hemorrhage trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Postpartum Hemorrhage appearing as the primary indexed condition, and to 1 intervention - of which Tranexamic Acid is the first listed.
NCT03287336 reports a single indexed study location in District of Columbia.
Frequently Asked Questions
What is clinical trial NCT03287336 about?
NCT03287336 is a clinical study titled "Prevention of Postpartum Hemorrhage With Tranexamic Acid". Postpartum hemorrhage is a significant contributor to maternal morbidity and mortality and is worldwide. TXA has recently been proven to reduce mortality when given to women in setting of diagnosed PPH. US obstetricians and anesthesiologists are hesitant to use TXA in the peripartum period especiall...
What is the current status of trial NCT03287336?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 43 participants. The study started on 2018-01-02. Estimated completion is 2023-09-30.
What conditions does trial NCT03287336 study?
This clinical trial studies the following conditions: Postpartum Hemorrhage.
What interventions are being tested in trial NCT03287336?
The interventions under investigation include: Tranexamic Acid (DRUG).
Who is sponsoring clinical trial NCT03287336?
This trial is sponsored by George Washington University, which has 133 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03287336 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postpartum Hemorrhage
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03287336's enrollment target sits among peer trials
43 16th of 19 higher than 4 of 19 other Postpartum Hemorrhage trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postpartum Hemorrhage trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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