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NCT03281629 · ClinicalTrials.gov registry record · NA

Circuitry-Guided Smoking Cessation in Schizophrenia

A NA study, sponsored by University of Maryland, Baltimore.

Completed
Registry status
NA
Development phase
44
Enrollment target

NCT03281629: Completed NA study, sponsored by University of Maryland, Baltimore.

NCT03281629 is a NA study that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 44 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03281629, a NA study, has completed, sponsored by University of Maryland, Baltimore.

COMPLETED
Registry status
NA
Development phase
44 participants
Enrollment target

Study Summary

In a double-blinded, randomized, parallel controlled design, patients with schizophrenia spectrum disorder will be exposed to active or sham repetitive transcranial magentic stimulation (TMS) which was guided by functional magnetic resonance image (MRI). Smoking reduction/cessation and brain functional connectivity changes will be assessed at baseline, different stages of rTMS and/or follow-ups.

Primary Outcome

Cigarette per day (CPD) is measured to index smoking reduction and cessation. The change of CPD between baseline and end-of-treatment (1-month time point), 3-month follow up (4-month time point) and 6-month follow up (7-month time point) are reported. Negative values of the change of CPD indicate reductions in cigarette consumption.

Interventions

  • DEVICE Active TMS stimulation
  • DEVICE Sham TMS stimulation

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2018-10-19
Est. Completion 2022-02-15
Phase NA
University of Maryland, Baltimore

560 total trials

What the finished NCT03281629 record still lists

NCT03281629 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which Active TMS stimulation is the first listed.

NCT03281629 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03281629 about?

NCT03281629 is a clinical study titled "Circuitry-Guided Smoking Cessation in Schizophrenia". In a double-blinded, randomized, parallel controlled design, patients with schizophrenia spectrum disorder will be exposed to active or sham repetitive transcranial magentic stimulation (TMS) which was guided by functional magnetic resonance image (MRI). Smoking reduction/cessation and brain functio...

What is the current status of trial NCT03281629?

This trial is currently completed. It is a NA study. The enrollment target is 44 participants. The study started on 2018-10-19. Estimated completion is 2022-02-15.

What interventions are being tested in trial NCT03281629?

The interventions under investigation include: Active TMS stimulation (DEVICE), Sham TMS stimulation (DEVICE).

Who is sponsoring clinical trial NCT03281629?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03281629's enrollment target sits among peer trials

44 1423rd of 2000 higher than 566 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03281629, the US trial registry maintained by the National Library of Medicine. NCT03281629 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.