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NCT03277521 · ClinicalTrials.gov registry record · NA
Theta Burst Stimulation to Promote Motor Re-education in Tetraplegia
A NA study, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- NA
- Development phase
- 19
- Enrollment target
NCT03277521: Completed NA study, sponsored by Virginia Commonwealth University.
NCT03277521 is a NA study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 19 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03277521, a NA study, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- NA
- Development phase
- 19 participants
- Enrollment target
Study Summary
A repetitive, non-invasive brain stimulation technique referred to as theta burst stimulation can modulate corticomotor excitability and therefore has great rehabilitative potential for individuals with neurologic deficits, including individuals with spinal cord injury (SCI). In particular, intermittent theta burst stimulation (iTBS) can increase corticomotor excitability and may be a useful adjunct to physical rehabilitation to promote motor re-education after upper limb reconstruction in individuals with tetraplegia. Upper limb reconstruction involves surgical transfer of a non-paralyzed tendon or nerve with a redundant or less important function to perform a more critical function. Upper limb reconstruction is intended to help individuals achieve their goals related to activities of daily living and independence in the community. Outcomes after reconstruction are variable and depend largely on the efficacy of motor re-education of the transferred muscle to perform a new function. The long-term goal of our research is to determine whether iTBS combined with physical rehabilitation can improve motor re-education after reconstruction. As a first step, the purpose of this proposal is to determine the effect of iTBS on corticomotor excitability of proximal muscles in nonimpaired individuals and two groups of individuals with tetraplegia: individuals with and without upper limb reconstruction.
Primary Outcome
Corticomotor excitability will be measured via motor evoked potential amplitudes in response to transcranial magnetic stimulation
Interventions
- OTHER Intermittent theta burst stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2018-04-16 |
| Est. Completion | 2020-02-28 |
| Phase | NA |
What the finished NCT03277521 record still lists
NCT03277521 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Intermittent theta burst stimulation is the first listed.
NCT03277521 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03277521 about?
NCT03277521 is a clinical study titled "Theta Burst Stimulation to Promote Motor Re-education in Tetraplegia". A repetitive, non-invasive brain stimulation technique referred to as theta burst stimulation can modulate corticomotor excitability and therefore has great rehabilitative potential for individuals with neurologic deficits, including individuals with spinal cord injury (SCI). In particular, intermit...
What is the current status of trial NCT03277521?
This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2018-04-16. Estimated completion is 2020-02-28.
What interventions are being tested in trial NCT03277521?
The interventions under investigation include: Intermittent theta burst stimulation (OTHER).
Who is sponsoring clinical trial NCT03277521?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03277521's enrollment target sits among peer trials
19 1861st of 2000 higher than 138 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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