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NCT03277209 · ClinicalTrials.gov registry record · Phase 1

To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas

A Phase 1 study, sponsored by Weill Medical College of Cornell University.

Terminated
Registry status
Phase 1
Development phase
2
Enrollment target

NCT03277209 is a Phase 1 study that was terminated before completion, run by Weill Medical College of Cornell University. The registered enrollment target is 2 participants.

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The verdict

NCT03277209, a Phase 1 study, was terminated before completion, sponsored by Weill Medical College of Cornell University.

TERMINATED
Registry status
Phase 1
Development phase
2 participants
Enrollment target

Study Summary

A dose escalation trial to assess the safety of plerixafor in patients with advanced pancreatic, high grade serous ovarian and colorectal cancer. To identify the proof of mechanism, by demonstrating alterations in T-cell tumour distribution, ideally associated with loss of tumour cells, measured by immunostaining, and changes in FDG uptake.

Interventions

  • DRUG Plerixafor

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2017-07-25
Est. Completion 2019-12-30
Phase Phase 1

What the Registry Record Tells You About NCT03277209

The ClinicalTrials.gov registry entry for NCT03277209 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 2 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Weill Medical College of Cornell University, which has 701 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Plerixafor is the first listed.

NCT03277209 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03277209 about?

NCT03277209 is a clinical study titled "To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas". A dose escalation trial to assess the safety of plerixafor in patients with advanced pancreatic, high grade serous ovarian and colorectal cancer. To identify the proof of mechanism, by demonstrating alterations in T-cell tumour distribution, ideally associated with loss of tumour cells, measured by ...

What is the current status of trial NCT03277209?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 2 participants. The study started on 2017-07-25. Estimated completion is 2019-12-30.

What interventions are being tested in trial NCT03277209?

The interventions under investigation include: Plerixafor (DRUG).

Who is sponsoring clinical trial NCT03277209?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.