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NCT03274310 · ClinicalTrials.gov registry record · NA

FluSAFE: Flu SMS Alerts to Freeze Exposure

A NA study, sponsored by Columbia University.

Completed
Registry status
NA
Development phase
1,918
Enrollment target

NCT03274310: Completed NA study, sponsored by Columbia University.

NCT03274310 is a NA study that has completed, run by Columbia University. The registered enrollment target is 1,918 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (37% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03274310, a NA study, has completed, sponsored by Columbia University.

COMPLETED
Registry status
NA
Development phase
1,918 participants
Enrollment target

Study Summary

Influenza infection results in an estimated 31 million outpatient visits, 55,000 to 974,200 hospitalizations, and 3,000 to 49,000 deaths. Membership in household in which someone else has influenza is the major risk factor for contracting influenza. The household secondary attack rate (SAR) is as high as 19% based on laboratory-confirmed influenza and 30% based on symptoms. Non-pharmaceutical preventive measures, including education, may play a role in decreasing transmission, but are only effective if started within 36 hours of symptom onset in index cases. Yet, most interventions are delayed because they are not initiated until care is sought. The investigators have demonstrated in one primarily Latino, urban community sample, that text messaging can be used to rapidly identify community members with influenza-like illness (ILI) early in an illness. This early identification would enable implementation of an educational intervention in the optimal time frame to reduce influenza transmission. Providing education within a text message is a proven successful strategy to influence behavior. Text messaging itself is scalable, low-cost, and can be used in low literacy populations. However, using text-message based surveillance to trigger a real-time text-message behavioral educational intervention to decrease household influenza transmission has not been assessed.

Primary Outcome

One self-swab of the index case and self-swabs of other household members will be analyzed using reverse transcription polymerase chain reaction (RT-PCR) to identify household transmission of laboratory-confirmed influenza.

Interventions

  • BEHAVIORAL Educational text messages

Trial Details

FieldValue
Enrollment Target 1,918 participants
Start Date 2017-10-06
Est. Completion 2021-05-15
Phase NA
Columbia University

958 total trials

What the finished NCT03274310 record still lists

NCT03274310 is an interventional study that assigns participants to a tested intervention. Its 1,918 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (37% higher).

The record links to 0 conditions, and to 1 intervention - of which Educational text messages is the first listed.

NCT03274310 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03274310 about?

NCT03274310 is a clinical study titled "FluSAFE: Flu SMS Alerts to Freeze Exposure". Influenza infection results in an estimated 31 million outpatient visits, 55,000 to 974,200 hospitalizations, and 3,000 to 49,000 deaths. Membership in household in which someone else has influenza is the major risk factor for contracting influenza. The household secondary attack rate (SAR) is as hi...

What is the current status of trial NCT03274310?

This trial is currently completed. It is a NA study. The enrollment target is 1,918 participants. The study started on 2017-10-06. Estimated completion is 2021-05-15.

What interventions are being tested in trial NCT03274310?

The interventions under investigation include: Educational text messages (BEHAVIORAL).

Who is sponsoring clinical trial NCT03274310?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03274310's enrollment target sits among peer trials

1,918 55th of 2000 higher than 1,946 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03274310, the US trial registry maintained by the National Library of Medicine. NCT03274310 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.