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NCT03271528 · ClinicalTrials.gov registry record · Phase 1
Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers
A Phase 1 study, sponsored by Boston Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 66
- Enrollment target
NCT03271528: Completed Phase 1 study, sponsored by Boston Medical Center.
NCT03271528 is a Phase 1 study that has completed, run by Boston Medical Center. The registered enrollment target is 66 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03271528, a Phase 1 study, has completed, sponsored by Boston Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 66 participants
- Enrollment target
Study Summary
This is a double-blind, randomized, placebo-controlled, crossover design trial tested the effect of lacosamide on alcohol self-administration and craving following a priming dose of alcohol. The specific objective of this study was to determine whether lacosamide, a novel anticonvulsant that is FDA-approved for treating partial seizures, has effects on alcohol craving and consumption.
Primary Outcome
Alcohol consumption will be measured by using a graduated cylinder to determine the amount of alcohol given to the subject that was consumed. This outcome will be measured as standard drink units. A standard drink contains approximately 0.6 fluid ounces of pure alcohol.
Interventions
- DRUG Placebo oral capsule
- DRUG Lacosamide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2018-04-15 |
| Est. Completion | 2020-08-31 |
| Phase | Phase 1 |
What the finished NCT03271528 record still lists
NCT03271528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (10% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo oral capsule is the first listed.
NCT03271528 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03271528 about?
NCT03271528 is a clinical study titled "Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers". This is a double-blind, randomized, placebo-controlled, crossover design trial tested the effect of lacosamide on alcohol self-administration and craving following a priming dose of alcohol. The specific objective of this study was to determine whether lacosamide, a novel anticonvulsant that is FDA-...
What is the current status of trial NCT03271528?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 66 participants. The study started on 2018-04-15. Estimated completion is 2020-08-31.
What interventions are being tested in trial NCT03271528?
The interventions under investigation include: Placebo oral capsule (DRUG), Lacosamide (DRUG).
Who is sponsoring clinical trial NCT03271528?
This trial is sponsored by Boston Medical Center, which has 253 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03271528's enrollment target sits among peer trials
66 786th of 2000 higher than 1,203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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