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NCT03263819 · ClinicalTrials.gov registry record
Gastrointestinal Symptoms in Postural Orthostatic Tachycardia Syndrome
A clinical trial, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- 26
- Enrollment target
NCT03263819: Completed study, sponsored by Vanderbilt University Medical Center.
NCT03263819 is a clinical trial that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 26 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03263819 has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- 26 participants
- Enrollment target
Study Summary
Patients with POTS experience significant gastrointestinal symptoms. Current evidence suggesting that abnormal post-ganglionic sympathetic function could play a role in the pathophysiology of these GI abnormalities. Sympathetic fiber regulate motor and the postprandial GI peptides secretion. The focus of the present proposal is to determine glucose homeostasis, GI motility, and their association with GI and cardiovascular symptoms in POTS patients versus healthy controls. Furthermore, we will determine differences in these outcomes in POTS patients with and without evidence of postganglionic sympathetic fiber neuropathy. As a long-term goal, this study can lead us to understand the pathophysiology of common co-morbidities in patients with POTS to provide new treatment approaches and prevention strategies.
Primary Outcome
The plasma levels of GIP (Glucose-dependent insulinotropic polypeptide) ,GLP-1, C-peptide, insulin) and their pattern of secretion after ingestion of 75 g glucose. C peptide measured in pg/ml
Interventions
- DIAGNOSTIC_TEST Oral glucose tolerance test
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2017-06-20 |
| Est. Completion | 2020-12-31 |
What the finished NCT03263819 record still lists
NCT03263819 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 26 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Oral glucose tolerance test is the first listed.
NCT03263819 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03263819 about?
NCT03263819 is a clinical study titled "Gastrointestinal Symptoms in Postural Orthostatic Tachycardia Syndrome". Patients with POTS experience significant gastrointestinal symptoms. Current evidence suggesting that abnormal post-ganglionic sympathetic function could play a role in the pathophysiology of these GI abnormalities. Sympathetic fiber regulate motor and the postprandial GI peptides secretion. The fo...
What is the current status of trial NCT03263819?
This trial is currently completed. The enrollment target is 26 participants. The study started on 2017-06-20. Estimated completion is 2020-12-31.
What interventions are being tested in trial NCT03263819?
The interventions under investigation include: Oral glucose tolerance test (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03263819?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
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