Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03259230 · ClinicalTrials.gov registry record
Evaluation of IFNγ and Inflammatory Mediators in Patients With Malignancy-Associated Hemophagocytic Lymphohistiocytosis
A clinical trial of Hemophagocytic Lymphohistiocytosis, sponsored by Swedish Orphan Biovitrum.
- Completed
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT03259230: Completed study of Hemophagocytic Lymphohistiocytosis, sponsored by Swedish Orphan Biovitrum.
NCT03259230 is a study of Hemophagocytic Lymphohistiocytosis that has completed, run by Swedish Orphan Biovitrum. The registered enrollment target is 40 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03259230, a study of Hemophagocytic Lymphohistiocytosis, has completed, sponsored by Swedish Orphan Biovitrum.
- COMPLETED
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This observational study is designed to determine the levels of pro-inflammatory markers in patients diagnosed with M-HLH, and to assess whether the cytokine profiles bear an IFNγ signature.
Primary Outcome
Serum samples was collected at various times after HLH diagnosis to determine the concentration of CXCL10.
Conditions Studied
Interventions
- OTHER Data Collection
- OTHER Blood Draws
Study Locations (1)
Texas
- University of Texas MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2016-10-13 |
| Est. Completion | 2020-01-29 |
What the finished NCT03259230 record still lists
NCT03259230 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target.
The record links to 1 condition, with Hemophagocytic Lymphohistiocytosis appearing as the primary indexed condition, and to 2 interventions - of which Data Collection is the first listed.
NCT03259230 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT03259230 about?
NCT03259230 is a clinical study titled "Evaluation of IFNγ and Inflammatory Mediators in Patients With Malignancy-Associated Hemophagocytic Lymphohistiocytosis". This observational study is designed to determine the levels of pro-inflammatory markers in patients diagnosed with M-HLH, and to assess whether the cytokine profiles bear an IFNγ signature.
What is the current status of trial NCT03259230?
This trial is currently completed. The enrollment target is 40 participants. The study started on 2016-10-13. Estimated completion is 2020-01-29.
What conditions does trial NCT03259230 study?
This clinical trial studies the following conditions: Hemophagocytic Lymphohistiocytosis.
What interventions are being tested in trial NCT03259230?
The interventions under investigation include: Data Collection (OTHER), Blood Draws (OTHER).
Who is sponsoring clinical trial NCT03259230?
This trial is sponsored by Swedish Orphan Biovitrum, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03259230 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hemophagocytic Lymphohistiocytosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI