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NCT03248674 · ClinicalTrials.gov registry record
Diagnostic Performance of Coronary CT Angiography With CT FFR in Kidney Transplantation Candidates
A clinical trial, sponsored by Stanford University.
- Terminated
- Registry status
- 26
- Enrollment target
NCT03248674: Clinical Trial study, sponsored by Stanford University.
NCT03248674 is a clinical trial that was terminated before completion, run by Stanford University. The registered enrollment target is 26 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03248674 was terminated before completion, sponsored by Stanford University.
- TERMINATED
- Registry status
- 26 participants
- Enrollment target
Study Summary
Patients with chronic kidney disease (CKD) before kidney transplantation require that obstructive coronary artery disease (CAD) is excluded, as cardiovascular complications are the leading cause of mortality in kidney transplant patients. However, in this patient population, the optimal method for the detection of obstructive CAD has not been identified. Noninvasive stress tests such as Dobutamine stress echocardiography or nuclear perfusion study have low diagnostic accuracy. CT fractional flow reserve measurement (CT FFR) is a novel non-invasive (FDA approved) imaging test to identify obstructive CAD. The goal of this project is to evaluate the diagnostic accuracy of CT FFR in the detection of obstructive coronary artery disease in patients with chronic kidney disease before kidney transplantation.
Primary Outcome
Diagnostic accuracy of CT FFR (per vessel) in the detection of hemodynamically significant CAD as compared to invasive FFR derived from invasive coronary angiography (reference standard). Presence or absence of hemodynamically significant coronary artery disease in concordance between CT FFR and invasive FFR. Hemodynamically significant stenosis is defined as CT FFR value below 0.8.
Interventions
- DIAGNOSTIC_TEST CT FFR
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2017-08-28 |
| Est. Completion | 2020-01-24 |
Why NCT03248674 stopped before completion
NCT03248674 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 26 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which CT FFR is the first listed.
NCT03248674 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03248674 about?
NCT03248674 is a clinical study titled "Diagnostic Performance of Coronary CT Angiography With CT FFR in Kidney Transplantation Candidates". Patients with chronic kidney disease (CKD) before kidney transplantation require that obstructive coronary artery disease (CAD) is excluded, as cardiovascular complications are the leading cause of mortality in kidney transplant patients. However, in this patient population, the optimal method for t...
What is the current status of trial NCT03248674?
This trial is currently terminated. The enrollment target is 26 participants. The study started on 2017-08-28. Estimated completion is 2020-01-24.
What interventions are being tested in trial NCT03248674?
The interventions under investigation include: CT FFR (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03248674?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
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