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NCT03242473 · ClinicalTrials.gov registry record · NA
Comparing the Effects of Lactated Ringers and Normal Saline in Acute Pancreatitis
A NA study, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- NA
- Development phase
- 79
- Enrollment target
NCT03242473: Completed NA study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT03242473 is a NA study that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 79 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03242473, a NA study, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- NA
- Development phase
- 79 participants
- Enrollment target
Study Summary
Acute pancreatitis is increasingly common diagnosis in children. Most of the guidelines related to the details of management of acute pancreatitis are extrapolated from the adult literature. There is only limited data regarding management of acute pancreatitis in children. The mainstay of management is bowel and pancreatic rest with significant fluid support to minimize the effect of the cytokines on the pancreas and other organs. The standard fluid choices are Lactated Ringer's solution (LR) and normal saline (NS). Currently, both LR and NS are used at the discretion of the treating physician as the standard of care for acute pancreatitis. The investigators hope to examine the question of ideal fluid choice for fluid resuscitation in children with acute pancreatitis by assessing recovery time in the context of measured inflammatory markers and SIRS status at 24 and 48 hours after admission. The ideal fluid choice in the initial resuscitation of acute pancreatitis has not been effectively evaluated before in the pediatric population. Even if there is no statistically significant difference between the two fluid options, this trial will still provide clinically significant information.
Primary Outcome
Primary marker of inflammation, change measured at baseline and then every 24 hours for 48 hours
Interventions
- OTHER Fluid Management
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 79 participants |
| Start Date | 2014-12 |
| Est. Completion | 2020-10-23 |
| Phase | NA |
What the finished NCT03242473 record still lists
NCT03242473 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 79 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which Fluid Management is the first listed.
NCT03242473 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03242473 about?
NCT03242473 is a clinical study titled "Comparing the Effects of Lactated Ringers and Normal Saline in Acute Pancreatitis". Acute pancreatitis is increasingly common diagnosis in children. Most of the guidelines related to the details of management of acute pancreatitis are extrapolated from the adult literature. There is only limited data regarding management of acute pancreatitis in children. The mainstay of management...
What is the current status of trial NCT03242473?
This trial is currently completed. It is a NA study. The enrollment target is 79 participants. The study started on 2014-12. Estimated completion is 2020-10-23.
What interventions are being tested in trial NCT03242473?
The interventions under investigation include: Fluid Management (OTHER).
Who is sponsoring clinical trial NCT03242473?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03242473's enrollment target sits among peer trials
79 1060th of 2000 higher than 941 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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