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NCT03239418 · ClinicalTrials.gov registry record · NA
NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy
A NA study, sponsored by Brooks Rehabilitation.
- Terminated
- Registry status
- NA
- Development phase
- 26
- Enrollment target
NCT03239418: Clinical Trial NA study, sponsored by Brooks Rehabilitation.
NCT03239418 is a NA study that was terminated before completion, run by Brooks Rehabilitation. The registered enrollment target is 26 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03239418, a NA study, was terminated before completion, sponsored by Brooks Rehabilitation.
- TERMINATED
- Registry status
- NA
- Development phase
- 26 participants
- Enrollment target
Study Summary
Traumatic brain injury, stroke and other neurological conditions may result in weakness of the muscles that either open or close the eye. This is generally a result of impaired functioning of the oculomotor or facial cranial nerves. Current treatments to improve eye opening or closing are either invasive or largely ineffective. This study tests a noninvasive means of improving eyelid opening and closing by applying a previously demonstrated safe and effective neuromuscular electrical stimulation (NMES) intervention to the muscles controlling eyelid movement. Participants in this study will either receive the investigational NMES protocol 30 min per day for five days or a sham NMES for the same period. The primary outcome for this study is the participants' ability to open or close their affected eye. Secondary outcomes include additional measures of eye and corneal health.
Primary Outcome
Measure of eyelid function for participants with CN III or CN VII palsy
Interventions
- DEVICE Neuromuscular electrical stimulation
- DEVICE Sham neuromuscular electrical stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2017-01-06 |
| Est. Completion | 2019-10-16 |
| Phase | NA |
Why NCT03239418 stopped before completion
NCT03239418 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Neuromuscular electrical stimulation is the first listed.
NCT03239418 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03239418 about?
NCT03239418 is a clinical study titled "NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy". Traumatic brain injury, stroke and other neurological conditions may result in weakness of the muscles that either open or close the eye. This is generally a result of impaired functioning of the oculomotor or facial cranial nerves. Current treatments to improve eye opening or closing are either inv...
What is the current status of trial NCT03239418?
This trial is currently terminated. It is a NA study. The enrollment target is 26 participants. The study started on 2017-01-06. Estimated completion is 2019-10-16.
What interventions are being tested in trial NCT03239418?
The interventions under investigation include: Neuromuscular electrical stimulation (DEVICE), Sham neuromuscular electrical stimulation (DEVICE).
Who is sponsoring clinical trial NCT03239418?
This trial is sponsored by Brooks Rehabilitation, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03239418's enrollment target sits among peer trials
26 1710th of 2000 higher than 289 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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