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NCT03237091 · ClinicalTrials.gov registry record · NA

Enhancing Corticospinal Excitability to Improve Functional Recovery

A NA study, sponsored by Shepherd Center, Atlanta GA.

Completed
Registry status
NA
Development phase
19
Enrollment target

NCT03237091: Completed NA study, sponsored by Shepherd Center, Atlanta GA.

NCT03237091 is a NA study that has completed, run by Shepherd Center, Atlanta GA. The registered enrollment target is 19 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03237091, a NA study, has completed, sponsored by Shepherd Center, Atlanta GA.

COMPLETED
Registry status
NA
Development phase
19 participants
Enrollment target

Study Summary

Research indicates that increasing brain excitability might help improve hand function in people with spinal cord injury. Brain stimulation that uses electrodes placed on the surface of the scalp (also called "non-invasive brain stimulation") increases brain excitability and has the potential to make it easier for the brain and nervous system to respond to arm and hand training. The purpose of this study is to compare four different types of stimulation for increasing brain excitability to determine which types are best for helping people with tetraplegia improve their ability to use their arms and hands. To fully evaluate the value of brain stimulation on arm and hand function, the investigators will also evaluate the effect of sham (fake) stimulation. Each participant will receive a single session of each of the five types of stimulation being tested.

Primary Outcome

The motor control outcome measure evaluates how quickly the participant can move their fingers. Participants will tap their thumb or index finger as fast as possible for 10 seconds at a time while a sensor counts the number of taps. The strength outcome measure evaluates the participant's hand strength. Participants will use their thumb and index finger to pinch a hand-held device that measures their strength.

Interventions

  • OTHER bihemispheric transcranial pulsed current stimulation (tPCS)
  • OTHER unihemispheric transcranial pulsed current stimulation (tPCS)
  • OTHER bihemispheric transcranial direct current stimulation (tDCS)
  • OTHER unihemispheric transcranial direct current stimulation (tDCS)
  • OTHER sham-control

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2018-05-03
Est. Completion 2019-09-27
Phase NA
Shepherd Center, Atlanta GA

17 total trials

What the finished NCT03237091 record still lists

NCT03237091 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 5 interventions - of which bihemispheric transcranial pulsed current stimulation (tPCS) is the first listed.

NCT03237091 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03237091 about?

NCT03237091 is a clinical study titled "Enhancing Corticospinal Excitability to Improve Functional Recovery". Research indicates that increasing brain excitability might help improve hand function in people with spinal cord injury. Brain stimulation that uses electrodes placed on the surface of the scalp (also called "non-invasive brain stimulation") increases brain excitability and has the potential to mak...

What is the current status of trial NCT03237091?

This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2018-05-03. Estimated completion is 2019-09-27.

What interventions are being tested in trial NCT03237091?

The interventions under investigation include: bihemispheric transcranial pulsed current stimulation (tPCS) (OTHER), unihemispheric transcranial pulsed current stimulation (tPCS) (OTHER), bihemispheric transcranial direct current stimulation (tDCS) (OTHER), unihemispheric transcranial direct current stimulation (tDCS) (OTHER), sham-control (OTHER).

Who is sponsoring clinical trial NCT03237091?

This trial is sponsored by Shepherd Center, Atlanta GA, which has 17 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03237091's enrollment target sits among peer trials

19 1861st of 2000 higher than 138 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03237091, the US trial registry maintained by the National Library of Medicine. NCT03237091 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.