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NCT03226054 · ClinicalTrials.gov registry record · NA

Determining Risk Factors for Successful PPI Weaning

A NA study, sponsored by Mount Carmel Health System.

Terminated
Registry status
NA
Development phase
5
Enrollment target

NCT03226054 is a NA study that was terminated before completion, run by Mount Carmel Health System. The registered enrollment target is 5 participants.

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The verdict

NCT03226054, a NA study, was terminated before completion, sponsored by Mount Carmel Health System.

TERMINATED
Registry status
NA
Development phase
5 participants
Enrollment target

Study Summary

Gastroesophageal Reflux Disease ("GERD") can happen when stomach acid flows backward into your esophagus (tube from the mouth to the stomach), causing symptoms such as heartburn. Proton pump inhibitors (called "PPIs") are a type of medication that reduce acid in the stomach and are used to reduce the discomfort from GERD. Treatment for GERD with PPIs is recommended to last up to eight weeks; however, many people take them for longer periods. Some people are placed on PPIs (particularly in the hospital) to prevent ulcers and inflammation of the stomach, but they do not need to be on the medication long term. Previous research studies have shown that there are some risks with taking PPIs for a long time. These risks include the inability of your body to absorb some vitamins and minerals, certain infections such as pneumonia or the digestive tract infection called "C. diff," and possibly bone fractures. Therefore, it is desirable to stop taking a PPI when possible. The purpose of this study is to use a standard approach to help patients stop taking PPIs by adopting lifestyle habits known to reduce the symptoms of GERD while they slowly reduce their PPI dose. All medications used for this study are approved by the U.S. Food and Drug Administration ("FDA"). You are being asked to take part in this study because you have been taking a PPI for longer than the recommended time, and have either a diagnosis of GERD, gastritis, or an unclear indication for being on a PPI. About 100 patients from the Mount Carmel St. Ann's Family Medicine practice will participate in this research.

Interventions

  • BEHAVIORAL Lifestyle Modifications

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2016-09-01
Est. Completion 2018-10-01
Phase NA

Sponsor

Mount Carmel Health System

8 total trials

What the Registry Record Tells You About NCT03226054

The ClinicalTrials.gov registry entry for NCT03226054 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mount Carmel Health System, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Lifestyle Modifications is the first listed.

NCT03226054 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03226054 about?

NCT03226054 is a clinical study titled "Determining Risk Factors for Successful PPI Weaning". Gastroesophageal Reflux Disease ("GERD") can happen when stomach acid flows backward into your esophagus (tube from the mouth to the stomach), causing symptoms such as heartburn. Proton pump inhibitors (called "PPIs") are a type of medication that reduce acid in the stomach and are used to reduce th...

What is the current status of trial NCT03226054?

This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2016-09-01. Estimated completion is 2018-10-01.

What interventions are being tested in trial NCT03226054?

The interventions under investigation include: Lifestyle Modifications (BEHAVIORAL).

Who is sponsoring clinical trial NCT03226054?

This trial is sponsored by Mount Carmel Health System, which has 8 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.