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NCT03225755 · ClinicalTrials.gov registry record
Adipose Tissue and Circulating Markers of Inflammation in GH Deficiency and Changes With GH Therapy
A clinical trial, sponsored by Columbia University.
- Completed
- Registry status
- 7
- Enrollment target
NCT03225755: Completed study, sponsored by Columbia University.
NCT03225755 is a clinical trial that has completed, run by Columbia University. The registered enrollment target is 7 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03225755 has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 7 participants
- Enrollment target
Study Summary
In order to examine the effect of GH on adipose tissue inflammation, this study will examine adipose tissue and serum inflammation in patients with GH deficiency before and after GH therapy. The investigators will also obtain serum samples before and after treatment for adipokines, inflammatory markers and examine macrophages in circulation with regard to their inflammatory state. The investigators will also obtain adipose tissue biopsies from healthy subjects matched to the growth hormone deficiency (GHD) subjects. Adipose tissue specimens will be analyzed for adipose tissue morphology, adipocyte size, adipokine gene expression, and adipose tissue macrophage number.
Primary Outcome
Relative gene expression values of cluster of differentiation (CD68) gene in adipose tissue
Interventions
- DRUG Growth hormone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2017-08-01 |
| Est. Completion | 2025-04-30 |
What the finished NCT03225755 record still lists
NCT03225755 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 7 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Growth hormone is the first listed.
NCT03225755 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03225755 about?
NCT03225755 is a clinical study titled "Adipose Tissue and Circulating Markers of Inflammation in GH Deficiency and Changes With GH Therapy". In order to examine the effect of GH on adipose tissue inflammation, this study will examine adipose tissue and serum inflammation in patients with GH deficiency before and after GH therapy. The investigators will also obtain serum samples before and after treatment for adipokines, inflammatory mark...
What is the current status of trial NCT03225755?
This trial is currently completed. The enrollment target is 7 participants. The study started on 2017-08-01. Estimated completion is 2025-04-30.
What interventions are being tested in trial NCT03225755?
The interventions under investigation include: Growth hormone (DRUG).
Who is sponsoring clinical trial NCT03225755?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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