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NCT03222570 · ClinicalTrials.gov registry record · Phase 2
An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression
A Phase 2 study, sponsored by University of Minnesota.
- Completed
- Registry status
- Phase 2
- Development phase
- 90
- Enrollment target
NCT03222570 is a Phase 2 study that has completed, run by University of Minnesota. The registered enrollment target is 90 participants.
The verdict
NCT03222570, a Phase 2 study, has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 90 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the effectiveness of two adaptive treatment strategies (ATSs) for adolescent depression. The ATSs include delivery of an evidence-based psychotherapy (interpersonal psychotherapy for depressed adolescents, IPT-A), systematic symptom monitoring, and an empirically-derived algorithm that specifies whether, when, and how to augment IPT-A. Two hundred depressed adolescents (age 12-18) will be recruited to participate in a 16-week sequential multiple assignment randomized trial conducted in outpatient community mental health clinics. Adolescents will be randomized to the IPT-A ATS condition or the community clinic's usual care (UC). Adolescents in the IPT-A ATS condition who are insufficient responders will be randomized a second time to the addition of a selective serotonin reuptake inhibitor (SSRI) or more intensive IPT-A (delivered twice per week). Research assessments will be administered at baseline and at weeks 4, 8, 12, 16, and 36.
Interventions
- OTHER Usual Care
- BEHAVIORAL Interpersonal Psychotherapy for Depressed Adolescents
- DRUG Selective Serotonin Reuptake Inhibitor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2018-02-26 |
| Est. Completion | 2024-04-28 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03222570
The ClinicalTrials.gov registry entry for NCT03222570 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Usual Care is the first listed.
NCT03222570 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03222570 about?
NCT03222570 is a clinical study titled "An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression". The purpose of this study is to evaluate the effectiveness of two adaptive treatment strategies (ATSs) for adolescent depression. The ATSs include delivery of an evidence-based psychotherapy (interpersonal psychotherapy for depressed adolescents, IPT-A), systematic symptom monitoring, and an empiric...
What is the current status of trial NCT03222570?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2018-02-26. Estimated completion is 2024-04-28.
What interventions are being tested in trial NCT03222570?
The interventions under investigation include: Usual Care (OTHER), Interpersonal Psychotherapy for Depressed Adolescents (BEHAVIORAL), Selective Serotonin Reuptake Inhibitor (DRUG).
Who is sponsoring clinical trial NCT03222570?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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