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NCT03214458 · ClinicalTrials.gov registry record · NA

Effects of Nasal High-flow Oxygen in Patients With an Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

A NA study, sponsored by Temple University.

Completed
Registry status
NA
Development phase
10
Enrollment target

NCT03214458: Completed NA study, sponsored by Temple University.

NCT03214458 is a NA study that has completed, run by Temple University. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03214458, a NA study, has completed, sponsored by Temple University.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

The investigators are looking at the effect of humidified nasal high-flow with oxygen (HNHF-O2) on air exchange during exacerbations of COPD. HNHF-O2 therapy may have beneficial effects in patients with severe breathing impairment that results in low oxygen in the blood. Some studies show that patients with low blood oxygen levels who use HFNC oxygen have lower rates of needing mechanical ventilation.

Primary Outcome

The need to intensify therapy because HNHF-O2 does not achieve the targeted oxygen saturation of ≥ 90% resulting in the need to intensify respiratory support

Interventions

  • DEVICE Nasal high flow

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2017-07-20
Est. Completion 2018-04-18
Phase NA
Temple University

163 total trials

What the finished NCT03214458 record still lists

NCT03214458 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Nasal high flow is the first listed.

NCT03214458 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03214458 about?

NCT03214458 is a clinical study titled "Effects of Nasal High-flow Oxygen in Patients With an Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)". The investigators are looking at the effect of humidified nasal high-flow with oxygen (HNHF-O2) on air exchange during exacerbations of COPD. HNHF-O2 therapy may have beneficial effects in patients with severe breathing impairment that results in low oxygen in the blood. Some studies show that patie...

What is the current status of trial NCT03214458?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2017-07-20. Estimated completion is 2018-04-18.

What interventions are being tested in trial NCT03214458?

The interventions under investigation include: Nasal high flow (DEVICE).

Who is sponsoring clinical trial NCT03214458?

This trial is sponsored by Temple University, which has 163 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03214458's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03214458, the US trial registry maintained by the National Library of Medicine. NCT03214458 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.