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NCT03206710 · ClinicalTrials.gov registry record
Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
A clinical trial of Asthma and Wheezing, sponsored by Oregon Health and Science University.
- Completed
- Registry status
- 395
- Enrollment target
- 2
- Study locations
NCT03206710 is a study of Asthma and Wheezing that has completed, run by Oregon Health and Science University. The registered enrollment target is 395 participants, below the 1,562-participant average among 374 other Asthma trials with a reported enrollment target (75% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT03206710, a study of Asthma and Wheezing, has completed, sponsored by Oregon Health and Science University.
- COMPLETED
- Registry status
- 395 participants
- Enrollment target
- 2
- Study locations
Study Summary
In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on offspring lung function and subsequent incidence of wheeze by 48% through 1 year of age. The investigators are currently completing a second RCT of vitamin C supplementation in pregnant smokers with more robust measures of pulmonary outcomes. The purpose of this ECHO application is to combine these 2 focused, interventional cohorts to allow critical longitudinal follow-up of respiratory outcomes in these children including the study of pulmonary function test (PFT) trajectories and incidence of recurrent wheeze/asthma from infancy through early adolescence in offspring of pregnant smokers randomized to vitamin C versus placebo.
Conditions Studied
Interventions
- OTHER No current intervention
Study Locations (2)
Indiana
- Indiana University - Indianapolis
Oregon
- Oregon Health and Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 395 participants |
| Start Date | 2017-06-01 |
| Est. Completion | 2024-12-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03206710
The ClinicalTrials.gov registry entry for NCT03206710 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 395 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,562-participant average among 374 other Asthma trials with a reported enrollment target (75% lower). The listed sponsor is Oregon Health and Science University, which has 546 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Asthma appearing as the primary indexed condition, and to 1 intervention - of which No current intervention is the first listed.
NCT03206710 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Indiana, Oregon.
Frequently Asked Questions
What is clinical trial NCT03206710 about?
NCT03206710 is a clinical study titled "Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation". In a randomized clinical trial (RCT) published in JAMA, the investigators have provided evidence that vitamin C supplementation (500 mg daily during pregnancy) ameliorates the effects of maternal smoking during pregnancy on offspring lung function and subsequent incidence of wheeze by 48% through 1 ...
What is the current status of trial NCT03206710?
This trial is currently completed. The enrollment target is 395 participants. The study started on 2017-06-01. Estimated completion is 2024-12-31.
What conditions does trial NCT03206710 study?
This clinical trial studies the following conditions: Asthma, Wheezing, Pulmonary Function, In Utero Nicotine.
What interventions are being tested in trial NCT03206710?
The interventions under investigation include: No current intervention (OTHER).
Who is sponsoring clinical trial NCT03206710?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03206710 being conducted?
This trial has 2 study locations across Indiana, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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