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NCT03201562 · ClinicalTrials.gov registry record · Phase 2
A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia
A Phase 2 study, sponsored by LENZ Therapeutics.
- Completed
- Registry status
- Phase 2
- Development phase
- 58
- Enrollment target
NCT03201562: Completed Phase 2 study, sponsored by LENZ Therapeutics.
NCT03201562 is a Phase 2 study that has completed, run by LENZ Therapeutics. The registered enrollment target is 58 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (56% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03201562, a Phase 2 study, has completed, sponsored by LENZ Therapeutics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 58 participants
- Enrollment target
Study Summary
To evaluate the safety and efficacy of PRX-100 compared with aceclidine alone and vehicle in the treatment of early to moderate presbyopia.
Primary Outcome
Proportion of subjects with at least a 3 line (15 letter) improvement in near visual acuity in the study eye at 1 hour post-treatment in the mITT population
Interventions
- DRUG Vehicle
- DRUG Aceclidine+tropicamide combination
- DRUG Aceclidine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2017-04-30 |
| Est. Completion | 2018-05-20 |
| Phase | Phase 2 |
What the finished NCT03201562 record still lists
NCT03201562 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (56% lower).
The record links to 0 conditions, and to 3 interventions - of which Vehicle is the first listed.
NCT03201562 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03201562 about?
NCT03201562 is a clinical study titled "A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia". To evaluate the safety and efficacy of PRX-100 compared with aceclidine alone and vehicle in the treatment of early to moderate presbyopia.
What is the current status of trial NCT03201562?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 58 participants. The study started on 2017-04-30. Estimated completion is 2018-05-20.
What interventions are being tested in trial NCT03201562?
The interventions under investigation include: Vehicle (DRUG), Aceclidine+tropicamide combination (DRUG), Aceclidine (DRUG).
Who is sponsoring clinical trial NCT03201562?
This trial is sponsored by LENZ Therapeutics, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03201562's enrollment target sits among peer trials
58 1135th of 2000 higher than 860 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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