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NCT03199729 · ClinicalTrials.gov registry record · NA
Aging and Mixed Perturbation Training to Reduce Falls in Locomotion
A NA study of Older Adults, sponsored by University of Illinois at Chicago.
- Active
- Registry status
- NA
- Development phase
- 600
- Enrollment target
- 1
- Study location
NCT03199729: Active NA study of Older Adults, sponsored by University of Illinois at Chicago.
NCT03199729 is a NA study of Older Adults that is active but no longer recruiting, run by University of Illinois at Chicago. The registered enrollment target is 600 participants, above the 199-participant average among 23 other Older Adults trials with a reported enrollment target (202% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03199729, a NA study of Older Adults, is active but no longer recruiting, sponsored by University of Illinois at Chicago.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
The long-term objective of this research is to develop an efficacious training paradigm to enhance older adults' defense mechanisms against falls and possibility reduce healthcare cost. The Centers for Disease Control and Prevention estimates the direct medical cost for fall related injuries to be $30 billion annually. Slips and trips combined account for more than 50% of the outdoor falls in community-dwelling older adults. These environmental perturbations are opposing in nature, with slips mainly resulting in backward falls and trips in forward falls. This project explores perturbation training through both slip and trip exposure based on the principles of motor learning. The project design consists of a randomized controlled trial to examine the ability of the central nervous system to mitigate the interference in stability control (if any) that is induced by opposing types of perturbations. It also introduces a novel combined slip and trip perturbation training paradigm to enhance one's ability to retain and generalize the acquired fall-prevention skills to both types of falls. Slips and trips induced on an over ground walkway will be used to prepare the motor system to improve stability control and vertical limb support to resist falls. The longer-term benefits of such combined perturbation training over exclusive slip-only or trip-only perturbation training in reducing both laboratory-induced and real life falls will also be assessed. The hypothesis of this study if supported by the results will provide an evidence-supported training protocol to reduce the fall-risk among community-dwelling older adults.
Primary Outcome
Perturbation is induced successfully and safely to reproduce inadvertent falls in a protective laboratory environment. Falls will be measured by the amount of body weight supported by the full-body harness system and measured by a load cell attached to this system. Instability of the body's COM and poor limb support prior to touchdown of the recovery step account for 90\~100% of subsequent falls (occurring \~500ms later) in both sit-to-stand-slip and in gait-slip, in the laboratory settings. Int
Conditions Studied
Interventions
- OTHER Slip-only training
- OTHER Trip-only training
- OTHER Combined slip+trip training
Study Locations (1)
Illinois
- University of Illinois at Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2017-08-01 |
| Est. Completion | 2025-12-31 |
| Phase | NA |
What the registry record for NCT03199729 still lists
NCT03199729 is an interventional study that assigns participants to a tested intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, above the 199-participant average among 23 other Older Adults trials with a reported enrollment target (202% higher).
The record links to 1 condition, with Older Adults appearing as the primary indexed condition, and to 3 interventions - of which Slip-only training is the first listed.
NCT03199729 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT03199729 about?
NCT03199729 is a clinical study titled "Aging and Mixed Perturbation Training to Reduce Falls in Locomotion". The long-term objective of this research is to develop an efficacious training paradigm to enhance older adults' defense mechanisms against falls and possibility reduce healthcare cost. The Centers for Disease Control and Prevention estimates the direct medical cost for fall related injuries to be $...
What is the current status of trial NCT03199729?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 600 participants. The study started on 2017-08-01. Estimated completion is 2025-12-31.
What conditions does trial NCT03199729 study?
This clinical trial studies the following conditions: Older Adults.
What interventions are being tested in trial NCT03199729?
The interventions under investigation include: Slip-only training (OTHER), Trip-only training (OTHER), Combined slip+trip training (OTHER).
Who is sponsoring clinical trial NCT03199729?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03199729 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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participants (enrollment target), bucketed by value
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