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NCT03196544 · ClinicalTrials.gov registry record · NA
Novel Behavioral Intervention to Enhance Social Connections in Anxiety and Depression
A NA study, sponsored by University of California, San Diego.
- Completed
- Registry status
- NA
- Development phase
- 75
- Enrollment target
NCT03196544: Completed NA study, sponsored by University of California, San Diego.
NCT03196544 is a NA study that has completed, run by University of California, San Diego. The registered enrollment target is 75 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03196544, a NA study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
Study Summary
The overall goal of this project is to develop a novel transdiagnostic behavioral treatment -- social approach training -- intended to enhance positive social connections in individuals with elevated anxiety and/or depression. Social relationship impairments are pervasive and debilitating consequences of anxiety and depression. Existing treatments have some beneficial impact on social functioning; however, many people continue to have few and/or poor quality relationships following treatment, even after experiencing symptom relief. This study will evaluate the effects of social approach training on the brain systems that have been shown to be important for establishing positive connections with others. Approximately 60 individuals (ages 18-55) seeking treatment for anxiety or depression will participate in this study. Participants will be randomly assigned with equal probability to one of two versions of social approach training (5 or 10 sessions) or a waitlist (assessment only) control group. Participants will be assessed at baseline and post-treatment and compared on measures assessing brain responses to social reward (primary outcome), as well as physiological, behavioral, and emotional responses to social reward (secondary outcomes). It is hypothesized that participants assigned to social approach training will display greater increases from pre- to post-treatment in activity in brain systems that regulate the processing of social reward (e.g., striatum) relative to participants in the control group. This study will also determine whether the 5- vs. 10-session versions of the treatment program result in meaningful differences, compared to each other, in how the brain responds to social reward.
Primary Outcome
Change from pre- to post-assessment in neural activation measured using functional magnetic resonance imaging (fMRI) during reward trials of the social incentive delay (SID) task
Interventions
- BEHAVIORAL Social Approach Training (5 sessions)
- BEHAVIORAL Social Approach Training (10 sessions)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2018-04-03 |
| Est. Completion | 2020-04-01 |
| Phase | NA |
What the finished NCT03196544 record still lists
NCT03196544 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Social Approach Training (5 sessions) is the first listed.
NCT03196544 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03196544 about?
NCT03196544 is a clinical study titled "Novel Behavioral Intervention to Enhance Social Connections in Anxiety and Depression". The overall goal of this project is to develop a novel transdiagnostic behavioral treatment -- social approach training -- intended to enhance positive social connections in individuals with elevated anxiety and/or depression. Social relationship impairments are pervasive and debilitating consequenc...
What is the current status of trial NCT03196544?
This trial is currently completed. It is a NA study. The enrollment target is 75 participants. The study started on 2018-04-03. Estimated completion is 2020-04-01.
What interventions are being tested in trial NCT03196544?
The interventions under investigation include: Social Approach Training (5 sessions) (BEHAVIORAL), Social Approach Training (10 sessions) (BEHAVIORAL).
Who is sponsoring clinical trial NCT03196544?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03196544's enrollment target sits among peer trials
75 1069th of 2000 higher than 919 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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