Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03191461 · ClinicalTrials.gov registry record

Myocardial Perfusion and Fibrosis in Cancer Survivors

A clinical trial, sponsored by Virginia Commonwealth University.

Completed
Registry status
7
Enrollment target

NCT03191461: Completed study, sponsored by Virginia Commonwealth University.

NCT03191461 is a clinical trial that has completed, run by Virginia Commonwealth University. The registered enrollment target is 7 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03191461 has completed, sponsored by Virginia Commonwealth University.

COMPLETED
Registry status
7 participants
Enrollment target

Study Summary

This is a cross-sectional pilot study. The investigators seek to obtain early information pertaining to the relationship between measurements of myocardial perfusion reserve and myocardial fibrosis after receipt of Anthracycline-based chemotherapy (≥2 years prior).

Primary Outcome

The myocardial perfusion reserve index (MPRI) will be measured noninvasively with adenosine stress CMR imaging after dual-bolus first-pass perfusion with gadolinium contrast. The slope of the myocardial signal intensity curve is computed and normalized by the slope of the blood pool signal intensity curve for both rest and stress. MPRI is calculated as the ratio of the stress slope divided by the rest slope.

Interventions

  • DIAGNOSTIC_TEST Adenosine stress test MRI

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2017-11-13
Est. Completion 2024-04-11
Virginia Commonwealth University

558 total trials

What the finished NCT03191461 record still lists

NCT03191461 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 7 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which Adenosine stress test MRI is the first listed.

NCT03191461 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03191461 about?

NCT03191461 is a clinical study titled "Myocardial Perfusion and Fibrosis in Cancer Survivors". This is a cross-sectional pilot study. The investigators seek to obtain early information pertaining to the relationship between measurements of myocardial perfusion reserve and myocardial fibrosis after receipt of Anthracycline-based chemotherapy (≥2 years prior).

What is the current status of trial NCT03191461?

This trial is currently completed. The enrollment target is 7 participants. The study started on 2017-11-13. Estimated completion is 2024-04-11.

What interventions are being tested in trial NCT03191461?

The interventions under investigation include: Adenosine stress test MRI (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT03191461?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03191461, the US trial registry maintained by the National Library of Medicine. NCT03191461 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.