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NCT03174366 · ClinicalTrials.gov registry record · Phase 3

Investigating the Use of Prolia (Denosumab) in the Treatment of Acute Charcot Neuroarthropathy

A Phase 3 study of Charcot Joint of Foot, sponsored by Western University of Health Sciences.

Completed
Registry status
Phase 3
Development phase
7
Enrollment target
1
Study location

NCT03174366 is a Phase 3 study of Charcot Joint of Foot that has completed, run by Western University of Health Sciences. The registered enrollment target is 7 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT03174366, a Phase 3 study of Charcot Joint of Foot, has completed, sponsored by Western University of Health Sciences.

COMPLETED
Registry status
Phase 3
Development phase
7 participants
Enrollment target
1
Study location

Study Summary

Charcot neuroarthropathy (CN) is a debilitating disease primarily affecting poorly controlled diabetic patients with peripheral neuropathy. The consequences of CN include ulcerations of the foot and ankle, osteomyelitis, and severe musculoskeletal deformity. These consequences frequently lead to below-knee amputation of the affected limb. Currently treatment options are limited, and no pharmaceutical treatment has been efficacious in the medical literature. The purpose of this pilot study is to investigate the potential of the medication denosumab for acute stage Charcot neuroarthropathy.

Conditions Studied

Interventions

  • DRUG Denosumab

Study Locations (1)

California

  • Western University of Health Sciences - Pomona

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2017-05-16
Est. Completion 2019-03-06
Phase Phase 3

What the Registry Record Tells You About NCT03174366

The ClinicalTrials.gov registry entry for NCT03174366 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Western University of Health Sciences, which has 16 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Charcot Joint of Foot appearing as the primary indexed condition, and to 1 intervention - of which Denosumab is the first listed.

NCT03174366 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03174366 about?

NCT03174366 is a clinical study titled "Investigating the Use of Prolia (Denosumab) in the Treatment of Acute Charcot Neuroarthropathy". Charcot neuroarthropathy (CN) is a debilitating disease primarily affecting poorly controlled diabetic patients with peripheral neuropathy. The consequences of CN include ulcerations of the foot and ankle, osteomyelitis, and severe musculoskeletal deformity. These consequences frequently lead to bel...

What is the current status of trial NCT03174366?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 7 participants. The study started on 2017-05-16. Estimated completion is 2019-03-06.

What conditions does trial NCT03174366 study?

This clinical trial studies the following conditions: Charcot Joint of Foot.

What interventions are being tested in trial NCT03174366?

The interventions under investigation include: Denosumab (DRUG).

Who is sponsoring clinical trial NCT03174366?

This trial is sponsored by Western University of Health Sciences, which has 16 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03174366 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.