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NCT03154307 · ClinicalTrials.gov registry record · NA
Repeated TMS at Low Frequencies to Reduce Seizure Occurrence
A NA study, sponsored by Baptist Health South Florida.
- Terminated
- Registry status
- NA
- Development phase
- 2
- Enrollment target
NCT03154307: Clinical Trial NA study, sponsored by Baptist Health South Florida.
NCT03154307 is a NA study that was terminated before completion, run by Baptist Health South Florida. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03154307, a NA study, was terminated before completion, sponsored by Baptist Health South Florida.
- TERMINATED
- Registry status
- NA
- Development phase
- 2 participants
- Enrollment target
Study Summary
Perform non-invasive neuro-navigated repeated Transcranial Magnetic Stimulation (rTMS) at low frequencies (LF) with the intent to reduce the occurrence of seizures over time (long-term protocol). Seizure reduction and improvements in the quality of life in patients with epilepsy will be associated with increased cortical inhibition resulting from the LF-rTMS sessions over time. This procedure using rTMS at low frequencies (LF-rTMS) between 0.5 and 1 Hz is a safe and painless method for noninvasive focal cortical brain stimulation, which will be evaluated in its efficacy at reducing/suppressing seizures. Accordingly, we propose a clinical trial in patients with epilepsy to test whether LF-rTMS can improve seizure suppression. The location of the presumed 3D source in the brain will be stimulated for few minutes (10 to 15 min.). With the same rTMS modality, we will also perform motor threshold mapping in conjunction with its fully integrated and compatible electroencephalography (EEG) module. Up to 100 individuals 18 to 80 years with epilepsy will be enrolled. In addition, a short-term protocol has been added to test whether LF-rTMS can reduce or suppress status epilepticus in medically refractory participants.
Primary Outcome
Seizure frequency was recorded by the caregiver in a journal at weeks 6 and 7 post rTMS treatment.
Interventions
- DEVICE Low frequency repeated TMS (LF-rTMS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2016-02-19 |
| Est. Completion | 2019-08-23 |
| Phase | NA |
Why NCT03154307 stopped before completion
NCT03154307 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Low frequency repeated TMS (LF-rTMS) is the first listed.
NCT03154307 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03154307 about?
NCT03154307 is a clinical study titled "Repeated TMS at Low Frequencies to Reduce Seizure Occurrence". Perform non-invasive neuro-navigated repeated Transcranial Magnetic Stimulation (rTMS) at low frequencies (LF) with the intent to reduce the occurrence of seizures over time (long-term protocol). Seizure reduction and improvements in the quality of life in patients with epilepsy will be associated w...
What is the current status of trial NCT03154307?
This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2016-02-19. Estimated completion is 2019-08-23.
What interventions are being tested in trial NCT03154307?
The interventions under investigation include: Low frequency repeated TMS (LF-rTMS) (DEVICE).
Who is sponsoring clinical trial NCT03154307?
This trial is sponsored by Baptist Health South Florida, which has 40 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03154307's enrollment target sits among peer trials
2 1997th of 2000 the lowest of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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