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NCT03149042 · ClinicalTrials.gov registry record

Validation of a Computed Tomography (CT) Based Fractional Flow Reserve (FFR) Software Using the 320 Detector Aquilion ONE CT Scanner.

A clinical trial, sponsored by State University of New York at Buffalo.

Completed
Registry status
75
Enrollment target

NCT03149042 is a clinical trial that has completed, run by State University of New York at Buffalo. The registered enrollment target is 75 participants.

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The verdict

NCT03149042 has completed, sponsored by State University of New York at Buffalo.

COMPLETED
Registry status
75 participants
Enrollment target

Study Summary

Coronary Computed Tomography Angiography (CCTA) contrast opacification gradients and FFR-CT estimation can aid in the severity estimation of significant atherosclerotic lesions. Currently, FFR-CT algorithms can only be optimized using theoretical models and can only be validated in large multi-center clinical trials. Using patient specific 3D printed coronary phantoms would allow optimization of FFR-CT algorithms with a measured validation technique without the need for large clinical trials. Thus the investigators believe that this study will result in a FFR-CT algorithm/method with a better predictability for arterial lesion severity than those existing on the market today. Flow measurements will be compared with: CT-FFR for both patients and phantoms, angio lab FFR measurements and 30 days follow-up. This pilot clinical study includes \~50 patients over a year and half at GVI.

Interventions

  • DIAGNOSTIC_TEST CCTA

Trial Details

FieldValue
Enrollment Target 75 participants
Start Date 2016-05-28
Est. Completion 2019-04-21

What the Registry Record Tells You About NCT03149042

The ClinicalTrials.gov registry entry for NCT03149042 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 75 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is State University of New York at Buffalo, which has 243 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which CCTA is the first listed.

NCT03149042 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03149042 about?

NCT03149042 is a clinical study titled "Validation of a Computed Tomography (CT) Based Fractional Flow Reserve (FFR) Software Using the 320 Detector Aquilion ONE CT Scanner.". Coronary Computed Tomography Angiography (CCTA) contrast opacification gradients and FFR-CT estimation can aid in the severity estimation of significant atherosclerotic lesions. Currently, FFR-CT algorithms can only be optimized using theoretical models and can only be validated in large multi-cente...

What is the current status of trial NCT03149042?

This trial is currently completed. The enrollment target is 75 participants. The study started on 2016-05-28. Estimated completion is 2019-04-21.

What interventions are being tested in trial NCT03149042?

The interventions under investigation include: CCTA (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT03149042?

This trial is sponsored by State University of New York at Buffalo, which has 243 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.