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NCT03142191 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis

A Phase 2 study, sponsored by Celgene.

Terminated
Registry status
Phase 2
Development phase
138
Enrollment target

NCT03142191 is a Phase 2 study that was terminated before completion, run by Celgene. The registered enrollment target is 138 participants.

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The verdict

NCT03142191, a Phase 2 study, was terminated before completion, sponsored by Celgene.

TERMINATED
Registry status
Phase 2
Development phase
138 participants
Enrollment target

Study Summary

This is a Phase 2, multicenter, multinational, randomized, double-blind, placebo-controlled study evaluating the efficacy, safety, pharmacokinetics (PK), quality of life and exploratory pharmacodynamics (PD) of two treatment doses of CC-90001, 200 mg and 400 mg, compared with placebo, when delivered once daily per os (PO) in subjects with idiopathic pulmonary fibrosis (IPF). This study is designed to assess response to treatment by using measures of lung function, disease progression, fibrosis on radiography, and patient-reported outcomes. It will also assess dose response.

Interventions

  • OTHER Placebo
  • DRUG CC-90001

Trial Details

FieldValue
Enrollment Target 138 participants
Start Date 2017-07-26
Est. Completion 2021-12-24
Phase Phase 2

Sponsor

Celgene

308 total trials

What the Registry Record Tells You About NCT03142191

The ClinicalTrials.gov registry entry for NCT03142191 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 138 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Celgene, which has 308 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT03142191 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03142191 about?

NCT03142191 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis". This is a Phase 2, multicenter, multinational, randomized, double-blind, placebo-controlled study evaluating the efficacy, safety, pharmacokinetics (PK), quality of life and exploratory pharmacodynamics (PD) of two treatment doses of CC-90001, 200 mg and 400 mg, compared with placebo, when delivered...

What is the current status of trial NCT03142191?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 138 participants. The study started on 2017-07-26. Estimated completion is 2021-12-24.

What interventions are being tested in trial NCT03142191?

The interventions under investigation include: Placebo (OTHER), CC-90001 (DRUG).

Who is sponsoring clinical trial NCT03142191?

This trial is sponsored by Celgene, which has 308 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.