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NCT03137381 · ClinicalTrials.gov registry record · Phase 2
Study to Evaluate the Safety and Efficacy of CTP-543 in Adults With Moderate to Severe Alopecia Areata
A Phase 2 study, sponsored by Concert Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 149
- Enrollment target
NCT03137381: Completed Phase 2 study, sponsored by Concert Pharmaceuticals.
NCT03137381 is a Phase 2 study that has completed, run by Concert Pharmaceuticals. The registered enrollment target is 149 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (12% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03137381, a Phase 2 study, has completed, sponsored by Concert Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 149 participants
- Enrollment target
Study Summary
This study will evaluate the safety and efficacy of CTP-543 on hair loss in adults with chronic, moderate to severe alopecia areata.
Primary Outcome
The SALT is a quantitative assessment of scalp hair loss. SALT scores range in severity from 0 (no hair loss) to a maximum of 100 (complete hair loss). Responders were defined as participants achieving at least a 50% relative reduction in SALT score from baseline at Week 24.
Interventions
- DRUG CTP-543
- DRUG CTP-543 matching placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 149 participants |
| Start Date | 2017-08-09 |
| Est. Completion | 2019-07-08 |
| Phase | Phase 2 |
What the finished NCT03137381 record still lists
NCT03137381 is an interventional study that assigns participants to a tested intervention. The registered 149 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (12% higher).
The record links to 0 conditions, and to 2 interventions - of which CTP-543 is the first listed.
NCT03137381 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03137381 about?
NCT03137381 is a clinical study titled "Study to Evaluate the Safety and Efficacy of CTP-543 in Adults With Moderate to Severe Alopecia Areata". This study will evaluate the safety and efficacy of CTP-543 on hair loss in adults with chronic, moderate to severe alopecia areata.
What is the current status of trial NCT03137381?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 149 participants. The study started on 2017-08-09. Estimated completion is 2019-07-08.
What interventions are being tested in trial NCT03137381?
The interventions under investigation include: CTP-543 (DRUG), CTP-543 matching placebo (DRUG).
Who is sponsoring clinical trial NCT03137381?
This trial is sponsored by Concert Pharmaceuticals, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03137381's enrollment target sits among peer trials
149 491st of 2000 higher than 1,510 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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