Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections

NCT03137173 · View on ClinicalTrials.gov ↗

Study Summary

This was a randomized, double-blind, active-controlled, parallel-group, multicenter study in adult hospitalized patients to establish the safety and efficacy of ceftobiprole medocaril compared with vancomycin plus aztreonam in the treatment of acute bacterial skin and skin structure infections (ABSSSIs).

Interventions

  • DRUG ceftobiprole medocaril
  • DRUG vancomycin+aztreonam

Study Locations (20)

California

  • Physician Alliance Research Center — Anaheim
  • Saint Joseph's Clinical Research — Anaheim
  • eStudySite - Chula Vista - PPDS — Chula Vista
  • Central Valley Research LLC — Fresno
  • Marvel Clinical Research — Huntington Beach
  • eStudySite - La Mesa - PPDS — La Mesa
  • Omnibus Clinical Research — La Palma
  • Alliance Research LLC — Long Beach
  • Long Beach Clinical Trials — Long Beach
  • Central Valley Research, LLC — Modesto

Other

  • University Multiprofile Hospital for Active Treatment — Pleven
  • University Multiprofile Hospital for Active Treatment — Plovdiv
  • University Multiprofile Hospital for Active Treatment — Rousse
  • "University Multiprofile Hospital for Active Treatment and Emergency Medicine ""N. I. Pirogov"", Clinic of Purulent-Septic Surgery-"N.I. Pirogov"" — Sofia

Florida

  • Gonzalez MD and Aswad MD Health Services — Coral Gables
  • L&C Professional Medical Research Institute — Miami

Nevada

  • eStudySite - Las Vegas - PPDS — Las Vegas
  • Excel Clinical Research — Las Vegas

Montana

  • Mercury Street Medical Group — Butte

New Jersey

  • South Jersey Infectious Disease — Somers Point

Trial Details

FieldValue
Enrollment Target 679 participants
Start Date 2018-02-19
Est. Completion 2019-04-22
Phase Phase 3

Sponsor

Basilea Pharmaceutica

9 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03137173

The ClinicalTrials.gov registry entry for NCT03137173 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 679 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Basilea Pharmaceutica, which has 9 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Acute Bacterial Skin and Skin Structure Infections appearing as the primary indexed condition, and to 2 interventions — of which ceftobiprole medocaril is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03137173 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Other, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03137173 about?

NCT03137173 is a clinical study titled "Ceftobiprole in the Treatment of Patients With Acute Bacterial Skin and Skin Structure Infections". This was a randomized, double-blind, active-controlled, parallel-group, multicenter study in adult hospitalized patients to establish the safety and efficacy of ceftobiprole medocaril compared with vancomycin plus aztreonam in the treatment of acute bacterial skin and skin structure infections (ABSS...

What is the current status of trial NCT03137173?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 679 participants. The study started on 2018-02-19. Estimated completion is 2019-04-22.

What conditions does trial NCT03137173 study?

This clinical trial studies the following conditions: Acute Bacterial Skin and Skin Structure Infections. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03137173?

The interventions under investigation include: ceftobiprole medocaril (DRUG), vancomycin+aztreonam (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03137173?

This trial is sponsored by Basilea Pharmaceutica, which has 9 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03137173 being conducted?

This trial has 20 study locations across California, Florida, Montana, Nevada, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial