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NCT03130335 · ClinicalTrials.gov registry record · NA
Intra-articular Autologous Bone Marrow Aspirate Injection for Knee Osteoarthritis
A NA study, sponsored by Hospital for Special Surgery, New York.
- Completed
- Registry status
- NA
- Development phase
- 13
- Enrollment target
NCT03130335: Completed NA study, sponsored by Hospital for Special Surgery, New York.
NCT03130335 is a NA study that has completed, run by Hospital for Special Surgery, New York. The registered enrollment target is 13 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03130335, a NA study, has completed, sponsored by Hospital for Special Surgery, New York.
- COMPLETED
- Registry status
- NA
- Development phase
- 13 participants
- Enrollment target
Study Summary
Knee osteoarthritis (OA) is a leading cause of disability. The objectives of treatment are to reduce pain, improve function, and slow down further breakdown of the knee. Recently, research on nonsurgical treatment options for knee OA has increased significantly. One potential treatment of interest is the use of stem cell injections. Stem cells are one's own cells that have the ability to divide into other types of cells, and may cause regrowth of cartilage when injected into the knee. There have been few, but promising, studies that show improvements in pain and function with stem cell injections in those with knee OA. Therefore, more research is needed to identify patients who might benefit from this injection. This pilot study will look at changes in pain and function for 20 patients at 1, 3, 6, and 12 months after a stem cell injection into the knee. Patients will also undergo magnetic resonance imaging at 6 months and 12 months following the injection.
Primary Outcome
The KOOS Jr. measures patient-reported pain and function. The score ranges from 0-100, with 0 representing total knee disability and 100 representing perfect knee health.
Interventions
- PROCEDURE BMA Injection
- BIOLOGICAL BMA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2017-04-28 |
| Est. Completion | 2019-10-01 |
| Phase | NA |
What the finished NCT03130335 record still lists
NCT03130335 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which BMA Injection is the first listed.
NCT03130335 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03130335 about?
NCT03130335 is a clinical study titled "Intra-articular Autologous Bone Marrow Aspirate Injection for Knee Osteoarthritis". Knee osteoarthritis (OA) is a leading cause of disability. The objectives of treatment are to reduce pain, improve function, and slow down further breakdown of the knee. Recently, research on nonsurgical treatment options for knee OA has increased significantly. One potential treatment of interest i...
What is the current status of trial NCT03130335?
This trial is currently completed. It is a NA study. The enrollment target is 13 participants. The study started on 2017-04-28. Estimated completion is 2019-10-01.
What interventions are being tested in trial NCT03130335?
The interventions under investigation include: BMA Injection (PROCEDURE), BMA (BIOLOGICAL).
Who is sponsoring clinical trial NCT03130335?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03130335's enrollment target sits among peer trials
13 1911th of 2000 higher than 88 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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