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NCT03126968 · ClinicalTrials.gov registry record · Phase 2
Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies
A Phase 2 study, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- Phase 2
- Development phase
- 66
- Enrollment target
NCT03126968: Completed Phase 2 study, sponsored by University of Maryland, Baltimore.
NCT03126968 is a Phase 2 study that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 66 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03126968, a Phase 2 study, has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 66 participants
- Enrollment target
Study Summary
Bleeding poses potential for significant complication after transbronchial lung biopsies. The investigators hypothesize that prophylactic intrabronchial instillation of topical epinephrine will reduce the likelihood of bleeding. The investigators plan a double-blind, placebo controlled trial to evaluate this hypothesis.
Primary Outcome
Intra-procedural hemorrhage will be graded by the performing bronchoscopist according to the following scale: 1. No hemorrhage. 2. Mild hemorrhage - Any bleeding originating from the biopsy target airway requiring wedging of the bronchoscope or "in and out" motion in order to achieve hemostasis. 3. Moderate hemorrhage - Any bleeding originating from the biopsy target airway requiring in addition to maneuvering the bronchoscope application of iced saline or topical epinephrine or placing the pat
Interventions
- DRUG Placebos
- DRUG Topical epinephrine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2017-07-01 |
| Est. Completion | 2021-07-02 |
| Phase | Phase 2 |
What the finished NCT03126968 record still lists
NCT03126968 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (50% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebos is the first listed.
NCT03126968 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03126968 about?
NCT03126968 is a clinical study titled "Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies". Bleeding poses potential for significant complication after transbronchial lung biopsies. The investigators hypothesize that prophylactic intrabronchial instillation of topical epinephrine will reduce the likelihood of bleeding. The investigators plan a double-blind, placebo controlled trial to eval...
What is the current status of trial NCT03126968?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 66 participants. The study started on 2017-07-01. Estimated completion is 2021-07-02.
What interventions are being tested in trial NCT03126968?
The interventions under investigation include: Placebos (DRUG), Topical epinephrine (DRUG).
Who is sponsoring clinical trial NCT03126968?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03126968's enrollment target sits among peer trials
66 975th of 2000 higher than 1,014 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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