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NCT03126539 · ClinicalTrials.gov registry record · Phase 2
Effect of Topical Sulforaphane on Skin Fragility Seen in Skin Aging and With Ultraviolet Exposure
A Phase 2 study, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- Phase 2
- Development phase
- 9
- Enrollment target
NCT03126539: Clinical Trial Phase 2 study, sponsored by Johns Hopkins University.
NCT03126539 is a Phase 2 study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 9 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03126539, a Phase 2 study, was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 9 participants
- Enrollment target
Study Summary
This study aims to compare the expression of keratins before and after application of sulforaphane (SF) to determine whether this agent alters skin fragility seen in both intrinsic and extrinsic skin aging and UV light exposure.
Primary Outcome
Clinical assessment of mottled hyperpigmentation pre and post Sulforaphane (SF) treatment will be done for both photoprotected and photodamaged skin treated with sulforaphane. Mottled Hyperpigmentation Score system will be applied, with scale of 0 to 4, 4= clear improvement after 1 week of SF or placebo application.
Interventions
- DRUG Sulforaphane
- RADIATION Narrow-band Ultraviolet B exposure
- PROCEDURE 4 mm skin punch biopsy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2017-09-15 |
| Est. Completion | 2019-01-18 |
| Phase | Phase 2 |
Why NCT03126539 stopped before completion
NCT03126539 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 3 interventions - of which Sulforaphane is the first listed.
NCT03126539 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03126539 about?
NCT03126539 is a clinical study titled "Effect of Topical Sulforaphane on Skin Fragility Seen in Skin Aging and With Ultraviolet Exposure". This study aims to compare the expression of keratins before and after application of sulforaphane (SF) to determine whether this agent alters skin fragility seen in both intrinsic and extrinsic skin aging and UV light exposure.
What is the current status of trial NCT03126539?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 9 participants. The study started on 2017-09-15. Estimated completion is 2019-01-18.
What interventions are being tested in trial NCT03126539?
The interventions under investigation include: Sulforaphane (DRUG), Narrow-band Ultraviolet B exposure (RADIATION), 4 mm skin punch biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT03126539?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03126539's enrollment target sits among peer trials
9 1989th of 2000 higher than 11 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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