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NCT03123978 · ClinicalTrials.gov registry record · Phase 1

Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer

A Phase 1 study, sponsored by University of California, Davis.

Completed
Registry status
Phase 1
Development phase
6
Enrollment target

NCT03123978 is a Phase 1 study that has completed, run by University of California, Davis. The registered enrollment target is 6 participants.

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The verdict

NCT03123978, a Phase 1 study, has completed, sponsored by University of California, Davis.

COMPLETED
Registry status
Phase 1
Development phase
6 participants
Enrollment target

Study Summary

This phase I trial studies the best dose and side effects of niclosamide when given together with enzalutamide in treating patients with castration-resistant prostate cancer that has come back or has spread to other places in the body. Androgens can cause the growth of prostate cancer cells. Hormone therapy using enzalutamide may fight prostate cancer by lowering the amount of androgen the body makes and/or blocking the use of androgen by the tumor cells. Niclosamide may block signals that enhance prostate cancer cell growth. Giving enzalutamide and niclosamide may work better in treating patients with castration-resistant prostate cancer.

Interventions

  • DRUG Enzalutamide
  • DRUG Niclosamide

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2017-01-09
Est. Completion 2022-04-19
Phase Phase 1

Sponsor

University of California, Davis

657 total trials

What the Registry Record Tells You About NCT03123978

The ClinicalTrials.gov registry entry for NCT03123978 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Enzalutamide is the first listed.

NCT03123978 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03123978 about?

NCT03123978 is a clinical study titled "Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer". This phase I trial studies the best dose and side effects of niclosamide when given together with enzalutamide in treating patients with castration-resistant prostate cancer that has come back or has spread to other places in the body. Androgens can cause the growth of prostate cancer cells. Hormone...

What is the current status of trial NCT03123978?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2017-01-09. Estimated completion is 2022-04-19.

What interventions are being tested in trial NCT03123978?

The interventions under investigation include: Enzalutamide (DRUG), Niclosamide (DRUG).

Who is sponsoring clinical trial NCT03123978?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.