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NCT03091920 · ClinicalTrials.gov registry record · Phase 2
Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and Hypertension
A Phase 2 study, sponsored by Cyclerion Therapeutics.
- Completed
- Registry status
- Phase 2
- Development phase
- 26
- Enrollment target
NCT03091920: Completed Phase 2 study, sponsored by Cyclerion Therapeutics.
NCT03091920 is a Phase 2 study that has completed, run by Cyclerion Therapeutics. The registered enrollment target is 26 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03091920, a Phase 2 study, has completed, sponsored by Cyclerion Therapeutics.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 26 participants
- Enrollment target
Study Summary
To compare the safety, tolerability, pharmacokinetic (PK) profile, and pharmacodynamic (PD) effects of 2 treatment regimens of IW-1973 tablet (40 mg per day) administered orally for 2 weeks to patients with stable type 2 diabetes mellitus and hypertension.
Interventions
- DRUG Placebo
- DRUG IW-1973
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2017-02-28 |
| Est. Completion | 2017-08-03 |
| Phase | Phase 2 |
What the finished NCT03091920 record still lists
NCT03091920 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03091920 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03091920 about?
NCT03091920 is a clinical study titled "Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and Hypertension". To compare the safety, tolerability, pharmacokinetic (PK) profile, and pharmacodynamic (PD) effects of 2 treatment regimens of IW-1973 tablet (40 mg per day) administered orally for 2 weeks to patients with stable type 2 diabetes mellitus and hypertension.
What is the current status of trial NCT03091920?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 26 participants. The study started on 2017-02-28. Estimated completion is 2017-08-03.
What interventions are being tested in trial NCT03091920?
The interventions under investigation include: Placebo (DRUG), IW-1973 (DRUG).
Who is sponsoring clinical trial NCT03091920?
This trial is sponsored by Cyclerion Therapeutics, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03091920's enrollment target sits among peer trials
26 1708th of 2000 higher than 282 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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