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NCT03089645 · ClinicalTrials.gov registry record · Phase 1
MEDI5083 Alone and in Combination With Durvalumab, Tremelimumab, and/or Docetaxel.
A Phase 1 study, sponsored by MedImmune.
- Completed
- Registry status
- Phase 1
- Development phase
- 39
- Enrollment target
NCT03089645: Completed Phase 1 study, sponsored by MedImmune.
NCT03089645 is a Phase 1 study that has completed, run by MedImmune. The registered enrollment target is 39 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (35% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03089645, a Phase 1 study, has completed, sponsored by MedImmune.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 39 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety, pharmacokinetics and Immunogenicity of Medi5083 alone or in combination with Durvalumab,Tremelimumab, and/or Docetaxel in adult subjects with advanced solid tumors.
Primary Outcome
Safety Endpoint
Interventions
- BIOLOGICAL MEDI5083 monotherapy
- BIOLOGICAL MEID5083 with Durvalumab or Tremelimumab
- BIOLOGICAL Medi5083 with Durvalumab and Docetaxel
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2017-03-21 |
| Est. Completion | 2020-06-23 |
| Phase | Phase 1 |
What the finished NCT03089645 record still lists
NCT03089645 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (35% lower).
The record links to 0 conditions, and to 3 interventions - of which MEDI5083 monotherapy is the first listed.
NCT03089645 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03089645 about?
NCT03089645 is a clinical study titled "MEDI5083 Alone and in Combination With Durvalumab, Tremelimumab, and/or Docetaxel.". The purpose of this study is to evaluate the safety, pharmacokinetics and Immunogenicity of Medi5083 alone or in combination with Durvalumab,Tremelimumab, and/or Docetaxel in adult subjects with advanced solid tumors.
What is the current status of trial NCT03089645?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 39 participants. The study started on 2017-03-21. Estimated completion is 2020-06-23.
What interventions are being tested in trial NCT03089645?
The interventions under investigation include: MEDI5083 monotherapy (BIOLOGICAL), MEID5083 with Durvalumab or Tremelimumab (BIOLOGICAL), Medi5083 with Durvalumab and Docetaxel (BIOLOGICAL).
Who is sponsoring clinical trial NCT03089645?
This trial is sponsored by MedImmune, which has 210 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03089645's enrollment target sits among peer trials
39 1191st of 2000 higher than 804 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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