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NCT03088800 · ClinicalTrials.gov registry record · Phase 2
IBUPAP Study for Pain Management in Children
A Phase 2 study, sponsored by Antonios Likourezos.
- Completed
- Registry status
- Phase 2
- Development phase
- 90
- Enrollment target
NCT03088800: Completed Phase 2 study, sponsored by Antonios Likourezos.
NCT03088800 is a Phase 2 study that has completed, run by Antonios Likourezos. The registered enrollment target is 90 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03088800, a Phase 2 study, has completed, sponsored by Antonios Likourezos.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 90 participants
- Enrollment target
Study Summary
Current literature supports ibuprofen and APAP are the most commonly used analgesics in the pediatric ED for acute traumatic/non-traumatic pain. However, the analgesic benefits of combination ibuprofen and APAP in this specific setting does not exist, but instead only as it applies to pediatric patients with postoperative pain. Thus, we have designed a double-blind, randomized, controlled clinical trial to evaluate analgesic efficacy, safety and feasibility of combination therapy to potentially broaden its clinical application in the pediatric ED. The investigators' hypothesize that combination oral ibuprofen and APAP therapy is superior to either drug alone and is an excellent analgesic modality for controlling acute traumatic/non-traumatic pain in the pediatric ED.
Primary Outcome
Pain Score via Numeric Rating Scale or FACES pain scale at 60 minutes from baseline ( ranging from 0 to 10, with 0 being no pain, 5 being moderate pain, and 10 being very severe pain)
Interventions
- DRUG Ibuprofen
- DRUG APAP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2018-04-30 |
| Est. Completion | 2020-07-30 |
| Phase | Phase 2 |
What the finished NCT03088800 record still lists
NCT03088800 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 2 interventions - of which Ibuprofen is the first listed.
NCT03088800 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03088800 about?
NCT03088800 is a clinical study titled "IBUPAP Study for Pain Management in Children". Current literature supports ibuprofen and APAP are the most commonly used analgesics in the pediatric ED for acute traumatic/non-traumatic pain. However, the analgesic benefits of combination ibuprofen and APAP in this specific setting does not exist, but instead only as it applies to pediatric pati...
What is the current status of trial NCT03088800?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2018-04-30. Estimated completion is 2020-07-30.
What interventions are being tested in trial NCT03088800?
The interventions under investigation include: Ibuprofen (DRUG), APAP (DRUG).
Who is sponsoring clinical trial NCT03088800?
This trial is sponsored by Antonios Likourezos, which has 33 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03088800's enrollment target sits among peer trials
90 772nd of 2000 higher than 1,199 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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