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NCT03084471 · ClinicalTrials.gov registry record · Phase 3

An Open-Label, Multi-Centre, Study to Assess the Safety of Fixed-Dose Durvalumab + Tremelimumab Combination Therapy or Durvalumab Monotherapy in Advanced Solid Malignancies.

A Phase 3 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 3
Development phase
867
Enrollment target

NCT03084471 is a Phase 3 study that has completed, run by AstraZeneca. The registered enrollment target is 867 participants.

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The verdict

NCT03084471, a Phase 3 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 3
Development phase
867 participants
Enrollment target

Study Summary

To evaluate the safety, tolerability, and anti-tumor activity of the combination of durvalumab + tremelimumab or durvalumab alone in different solid tumors.

Interventions

  • BIOLOGICAL MEDI4736 (Durvalumab)
  • BIOLOGICAL MEDI4736 (Durvalumab) + Tremelimumab

Trial Details

FieldValue
Enrollment Target 867 participants
Start Date 2017-06-05
Est. Completion 2022-12-16
Phase Phase 3

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT03084471

The ClinicalTrials.gov registry entry for NCT03084471 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 867 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which MEDI4736 (Durvalumab) is the first listed.

NCT03084471 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03084471 about?

NCT03084471 is a clinical study titled "An Open-Label, Multi-Centre, Study to Assess the Safety of Fixed-Dose Durvalumab + Tremelimumab Combination Therapy or Durvalumab Monotherapy in Advanced Solid Malignancies.". To evaluate the safety, tolerability, and anti-tumor activity of the combination of durvalumab + tremelimumab or durvalumab alone in different solid tumors.

What is the current status of trial NCT03084471?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 867 participants. The study started on 2017-06-05. Estimated completion is 2022-12-16.

What interventions are being tested in trial NCT03084471?

The interventions under investigation include: MEDI4736 (Durvalumab) (BIOLOGICAL), MEDI4736 (Durvalumab) + Tremelimumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT03084471?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.