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NCT03075007 · ClinicalTrials.gov registry record
Brain Vascular Disease in Aging and Dementia
A clinical trial, sponsored by Columbia University.
- Completed
- Registry status
- 48
- Enrollment target
NCT03075007: Completed study, sponsored by Columbia University.
NCT03075007 is a clinical trial that has completed, run by Columbia University. The registered enrollment target is 48 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03075007 has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 48 participants
- Enrollment target
Study Summary
This study examines the factors that may drive the relationship between vascular disease and Alzheimer's Disease (AD) in a large, longitudinal, multi-ethnic community-based cohort study of older adults in northern Manhattan, New York. In past research, the investigators demonstrated that accumulation of brain vascular disease is associated with risk for development of AD. The study now extends the research to examine how brain vascular disease and AD interact. In this pilot study, the investigators will obtain positron emission tomography (PET) scans to measure amyloid (one of the protein pathological markers of AD) from participants in an ongoing community-based study of aging and dementia (WHICAP). The study will include subjects who are already enrolled in the parent project. Further, this study will enroll both subjects who have never been evaluated with PET scans and those who received a previous baseline PET scan. The study plans to obtain approximately 30 repeat amyloid PET scans and 20 baseline PET scans. The investigators will also conduct transcranial Doppler studies to measure blood flow in the participants with amyloid PET scans. The potential benefits to society should be considerable if this study reveals new information about risk factors for or contributions to AD.
Primary Outcome
The primary outcome is the mean standard uptake value ratio in the 4 regions of interest.
Interventions
- RADIATION Florbetaben F18
- PROCEDURE Transcranial Doppler
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2017-05-23 |
| Est. Completion | 2019-08-31 |
What the finished NCT03075007 record still lists
NCT03075007 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 48 participants, a relatively small participant target.
The record links to 0 conditions, and to 2 interventions - of which Florbetaben F18 is the first listed.
NCT03075007 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03075007 about?
NCT03075007 is a clinical study titled "Brain Vascular Disease in Aging and Dementia". This study examines the factors that may drive the relationship between vascular disease and Alzheimer's Disease (AD) in a large, longitudinal, multi-ethnic community-based cohort study of older adults in northern Manhattan, New York. In past research, the investigators demonstrated that accumulatio...
What is the current status of trial NCT03075007?
This trial is currently completed. The enrollment target is 48 participants. The study started on 2017-05-23. Estimated completion is 2019-08-31.
What interventions are being tested in trial NCT03075007?
The interventions under investigation include: Florbetaben F18 (RADIATION), Transcranial Doppler (PROCEDURE).
Who is sponsoring clinical trial NCT03075007?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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