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NCT03069911 · ClinicalTrials.gov registry record · Phase 1
Trial of OnabotulinumtoxinA for Depression in Parkinson Disease
A Phase 1 study, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 3
- Enrollment target
NCT03069911: Clinical Trial Phase 1 study, sponsored by Johns Hopkins University.
NCT03069911 is a Phase 1 study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03069911, a Phase 1 study, was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 3 participants
- Enrollment target
Study Summary
This study evaluates the efficacy of onabotulinumtoxinA (BOTOX®) in the treatment of depression associated with Idiopathic Parkinson Disease in adults. As a Randomized Controlled Trial, half of the participants will receive onabotulinumtoxinA injections and half will receive a placebo saline solution.
Primary Outcome
Improvement on a clinician-rated objective scale for depression as assessed over two weeks (6 weeks and 12 weeks after treatment)
Interventions
- BIOLOGICAL OnabotulinumtoxinA
- BIOLOGICAL Control
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2018-11-01 |
| Est. Completion | 2019-06-01 |
| Phase | Phase 1 |
Why NCT03069911 stopped before completion
NCT03069911 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which OnabotulinumtoxinA is the first listed.
NCT03069911 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03069911 about?
NCT03069911 is a clinical study titled "Trial of OnabotulinumtoxinA for Depression in Parkinson Disease". This study evaluates the efficacy of onabotulinumtoxinA (BOTOX®) in the treatment of depression associated with Idiopathic Parkinson Disease in adults. As a Randomized Controlled Trial, half of the participants will receive onabotulinumtoxinA injections and half will receive a placebo saline solutio...
What is the current status of trial NCT03069911?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2018-11-01. Estimated completion is 2019-06-01.
What interventions are being tested in trial NCT03069911?
The interventions under investigation include: OnabotulinumtoxinA (BIOLOGICAL), Control (BIOLOGICAL).
Who is sponsoring clinical trial NCT03069911?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03069911's enrollment target sits among peer trials
3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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